2-Chloro-6-propylsulfanylpyridine-4-carboxamide

Base Information

Chemical Name:2-Chloro-6-propylsulfanylpyridine-4-carboxamide
CAS No.:313269-84-0
Molecular Formula:C₉H₁₁ClN₂OS
Molecular Weight:230.718
Hs Code.:
DSSTox Substance ID:DTXSID50373059
Wikidata:Q82161184
Mol file:313269-84-0.mol

Synonyms:313269-84-0;2-CHLORO-6-(PROPYLTHIO)-4-PYRIDINECARBOXAMIDE;2-chloro-6-propylsulfanylpyridine-4-carboxamide;DTXSID50373059;AKOS004902587;FT-0611843

Suppliers and Price of 2-Chloro-6-propylsulfanylpyridine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-6-(PROPYLTHIO)-4-PYRIDINECARBOXAMIDE 95.00%
5MG
$ 498.81

Total 2 raw suppliers

Chemical Property of 2-Chloro-6-propylsulfanylpyridine-4-carboxamide

Chemical Property:

Vapor Pressure:3.1E-05mmHg at 25°C
Refractive Index:1.6
Boiling Point:355.5°C at 760 mmHg
PKA:14.05±0.50(Predicted)
Flash Point:168.8°C
PSA：82.27000
Density:1.32g/cm³
LogP:3.22020
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:230.0280618
Heavy Atom Count:14
Complexity:203

Purity/Quality:

98%Min ^*data from raw suppliers

2-CHLORO-6-(PROPYLTHIO)-4-PYRIDINECARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCSC1=NC(=CC(=C1)C(=O)N)Cl

Technology Process of 2-Chloro-6-propylsulfanylpyridine-4-carboxamide

There total 1 articles about 2-Chloro-6-propylsulfanylpyridine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 107-03-9
1-thiopropane

: 89281-13-0
2,6-dichloropyridine-4-carboxamide

: 313269-84-0
2-chloro-6-propylsulfanyl-isonicotinamide

Guidance literature:: With sodium methylate; In methanol; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.3390/50300208

Reference yield:

: 313269-84-0
2-chloro-6-propylsulfanyl-isonicotinamide

: 2-chloro-N-(2-hydroxy-phenyl)-6-propylsulfanyl-isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 77 percent / aq. NaOH / ethanol / Heating

2.1: SOCl₂ / benzene / 1 h / Heating

2.2: 44 percent / pyridine / acetone / 10 °C

With sodium hydroxide; thionyl chloride; In ethanol; benzene;
DOI:10.3390/60700603

Reference yield:

: 313269-84-0
2-chloro-6-propylsulfanyl-isonicotinamide

: 2-chloro-N-(5-chloro-2-hydroxy-phenyl)-6-propylsulfanyl-isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 77 percent / aq. NaOH / ethanol / Heating

2.1: SOCl₂ / benzene / 1 h / Heating

2.2: 53 percent / pyridine / acetone / 10 °C

With sodium hydroxide; thionyl chloride; In ethanol; benzene;
DOI:10.3390/60700603