89281-13-0

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dichloroisonicotinamide is used as a building block for the synthesis of various pharmaceutical products due to its antimicrobial, antiviral, and anticancer properties. It contributes to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
2,6-Dichloroisonicotinamide is used as an intermediate in the production of agrochemicals, where its biological activities can be harnessed to create effective compounds for agricultural use.
Used in Specialty Chemicals Production:
In addition to its applications in the pharmaceutical and agrochemical industries, 2,6-Dichloroisonicotinamide is also utilized as an intermediate in the production of other specialty chemicals, further expanding its range of applications across different industries.

InChI:InChI=1/C6H4Cl2N2O/c7-4-1-3(6(9)11)2-5(8)10-4/h1-2H,(H2,9,11)

Upstream product

• 101990-72-1 2,6-dichloro-pyridin-4-ylmethyl chloride 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 42521-08-4 2,6-dichloroisonicotinoyl chloride 
• 2402-78-0 2,6-dichloropyridine 
• 64-18-6 formic acid 
• 98027-84-0 2,6-dichloro-4-iodopyridine 
• 3019-71-4 Trichloroacetyl isocyanate 
• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 
• 7664-41-7 ammonia 

Downstream Products

• 32710-65-9 2,6-dichloro-4-cyanopyridine 
• 313269-84-0 2-chloro-6-propylsulfanyl-isonicotinamide 
• 88579-63-9 (2,6-dichloropyridin-4-yl)methanamine 
• 101990-69-6 (2,6-dichloropyridin-4-yl)methanol 

Relevant academic research and scientific papers

Synthesis of novel pyridine and pyrimidine derivatives as potential inhibitors of HIV-1 reverse transcriptase using palladium-catalysed C-N cross-coupling and nucleophilic aromatic substitution reactions

Palladium-mediated cross-coupling reactions are used in the successful construction of a small library of flexible heteroatom-linked diarylpyridine target compounds, including pyridines bearing a secondary amide substituent. Heteroatom-linked diarylpyrimidine derivatives bearing a chlorine substituent are prepared by base-catalysed nucleophilic aromatic substitution reactions without the need for palladium catalysis.

Preparation method of thiazine feed additives

The invention discloses a preparation method of thiazine feed additives and belongs to the technical field of feed additives. The technical scheme is shown in the description. Compared with the priorart, the method has the benefits as follows: the synthes

Preparation of primary amides from functionalized organozinc halides

Organozinc halides, which are prepared either by direct zinc insertion or halogen-magnesium exchange and subsequent transmetalation with ZnCl2, react smoothly with commercially available trichloroacetyl isocyanate to give, after hydrolysis, the corresponding primary amides. This method is compatible with a variety of functional groups such as an ester or a cyano group. Also heterocyclic-, alkenyl, and acetylenic zinc reagents are converted to the corresponding primary amides under these conditions.

Method for the protection of plants against diseases

Novel acylated urea derivatives of the general formula STR1 in which: X is hydrogen or halogen; Y is halogen; R1, R2 independently of one another are hydrogen, C1 -C6 alkyl or C1 -C6 alkyl which is substituted by halogen, cyano, C1 -C4 alkoxy or COO-C1 -C3 alkyl, or is C3 -C5 alkenyl or C3 -C5 alkenyl which is substituted by halogen, or is C3 -C5 alkynyl or C3 -C5 alkynyl which is substituted by halogen, or is C3 -C7 cycloalkyl or C3 -C7 cycloalkyl which is substituted by C1 -C2 alkyl, halogen, cyano or COO-C1 -C3 alkyl, or is phenyl, benzyl or phenyl or benzyl which are substituted by C1 -C3 alkyl, C1 -C3 alkoxy or halogen; and R1 can furthermore also be the radical Q or Q which is substituted by C1 -C3 alkyl, C3 -C7 cycloalkyl, C1 -C3 alkoxy or halogen, where Q can be bonded to the N atom via a C1 -C2 alkyl; or where R1 and R2 together with the adjacent N atom from a 3- to 7-membered heterocycle which can additionally contain 1 or 2 further hetero atoms such as O, N or S, and a carbonyl group and can be substituted by C1 -C3 alkyl, halogen or COO-C1 -C3 alkyl; Q is furan-2-yl, thiophen-2-yl, isoxazol-3-yl, isoxazol-3-yl, thiazol-2-yl, 1,2,4-thiadiazol-3-yl, 1,3,4-thiadiazol-2-yl, 2-, 3- or 4-pyridyl radicals or 2-, 3- or 4-pyridyl radicals which are substituted by C1 -C3 alkyl, C1 -C3 alkoxy, C1 -C3 alkylthio or halogen; 2-, 4- or 5-pyrimidyl radicals or 2-, 4- or 5-pyrimidyl radicals which are substituted by C1 -C3 alkyl, C1 -C3 alkoxy, C1 -C3 alkylthio, halogen or cyclopropyl. The novel active substances have plant-protecting properties and are suitable in particular for the preventive protection of plants against infection with phytopathogenic microorganisms, such as fungi, bacteria and viruses.