di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Base Information

Chemical Name:di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)
CAS No.:1374253-51-6
Molecular Formula:C₂₆H₃₂N₂O₆
Molecular Weight:468.55
Hs Code.:

Synonyms:di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Suppliers and Price of di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

There total 3 articles about di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 51560-21-5
1,4-diiodo-2,5-dimethoxybenzene

: 135884-31-0
N-boc-2-pyrroleboronic acid

: 1374253-51-6
di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 70 ℃; for 24h; Inert atmosphere;

Reference yield: 37.0%

: 117657-37-1
2-bromo-pyrrole-1-carboxylic acid tert-butyl ester

: (2,5-dimethoxy-1,4-phenylene)diboronic acid

: 1374253-51-6
di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In methanol; water; toluene; at 80 ℃; for 20h;
DOI:10.1039/c2cc17513d

Reference yield:

: 150-78-7
1,4-dimethoxybezene

: 1374253-51-6
di-tert-butyl 2,2'-(2,5-dimethoxy-1,4-phenylene)bis(1H-pyrrole-1-carboxylate)

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; periodic acid / methanol / 4 h / 70 °C / Inert atmosphere

2: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 24 h / 70 °C / Inert atmosphere

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; periodic acid; In methanol; N,N-dimethyl-formamide; 2: |Suzuki Coupling;