(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Base Information

Chemical Name:(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester
CAS No.:112113-89-0
Molecular Formula:C₂₃H₂₄N₈O₆
Molecular Weight:508.494
Hs Code.:

Synonyms:(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Suppliers and Price of (E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

There total 3 articles about (E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 89043-75-4
4-amino-4-deoxy-N¹⁰-formylpteroic acid

: 112113-86-7
dimethyl D,L-2-amino-4-hexanedioate hydrochloride

: 112113-89-0
(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Guidance literature:: With triethylamine; isobutyl chloroformate; In N,N-dimethyl-formamide;
DOI:10.1021/jm00399a013

Reference yield:

: 1117-71-1
methyl 4-bromocrotonate

: 112113-89-0
(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / LiN(Pr-i)2, HMPA / tetrahydrofuran / 0.5 h / -78 °C

2: 76 percent / aq. HCl / diethyl ether

3: 65 percent / Et₃N, i-BuOCOCl / dimethylformamide

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; triethylamine; lithium diisopropyl amide; isobutyl chloroformate; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00399a013

Reference yield:

: 112113-87-8
(E)-5-(Benzhydrylidene-amino)-hex-2-enedioic acid dimethyl ester

: 112113-89-0
(E)-5-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-amino]-benzoylamino}-hex-2-enedioic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / aq. HCl / diethyl ether

2: 65 percent / Et₃N, i-BuOCOCl / dimethylformamide

With hydrogenchloride; triethylamine; isobutyl chloroformate; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00399a013