4-carboxybenzediazonium tetrafluoroborate

Base Information

• Chemical Name: 4-carboxybenzediazonium tetrafluoroborate
• CAS No.: 456-25-7
• Molecular Formula: C7H5BF4N2O2
• Molecular Weight: 235.934
• Mol file: 456-25-7.mol

Synonyms:4-carboxybenzediazonium tetrafluoroborate

Chemical Property of 4-carboxybenzediazonium tetrafluoroborate

Chemical Property:

• PSA: 65.45000
• LogP: 3.16938

Purity/Quality:

99%, ^*data from raw suppliers

4-CARBOXYBENZENEDIAZONIUM TETRAFLUOROBORATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-carboxybenzediazonium tetrafluoroborate

There total 6 articles about 4-carboxybenzediazonium tetrafluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → p-carboxyphenyl diazonium tetrafluoroborate (456-25-7)

Guidance literature:

With tetrafluoroboric acid; sodium nitrite; In water;

DOI:10.1039/P19890000419

Reference yield: 85.0%

tetrafluoroboric acid + tert.-butylnitrite (540-80-7) + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → p-carboxyphenyl diazonium tetrafluoroborate (456-25-7)

Guidance literature:

In ethanol; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201802466

Reference yield: 55.0%

tetrafluoroboric acid + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + sodium nitrite (7632-00-0) → p-carboxyphenyl diazonium tetrafluoroborate (456-25-7)

Guidance literature:

In water; at 10 - 15 ℃; for 0.666667h;

upstream raw materials:

4-amino-benzoic acid

sodium nitrite

tert.-butylnitrite

sodium tetrafluoroborate

Downstream raw materials:

methyl (E)-4-carboxyl cinnamate

(C₆H₅)3SnC₆H₃(N(CH₃)2)NNC₆H₄COOH

4-(phenyltellanyl)benzoic acid

4-Fluorobenzoic acid

Refernces

• 1、 Yonezawa, Tetsu,Kawai, Koji,Kawakami, Hayato,Narushima, Takashi. "Preparation of water-dispersible palladium nanoparticles stabilized by carbon-palladium bonds and application to Suzuki-Miyaura coupling in water". . p. 1230 - 1232. Retrieved 2016.
• 2、 -. "Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation". Paragraph 0100-0101. . Retrieved 2019/01/04.
• 3、 Addy, Partha Sarathi,Erickson, Sarah B.,Italia, James S.,Chatterjee, Abhishek. "A Chemoselective Rapid Azo-Coupling Reaction (CRACR) for Unclickable Bioconjugation". supporting information. p. 11670 - 11673. Retrieved 2017/09/07.