ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate

Base Information

• Chemical Name: ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate
• CAS No.: 1043451-62-2
• Molecular Formula: C₁₉H₂₈O₅
• Molecular Weight: 336.428
• Mol file: 1043451-62-2.mol

Synonyms:ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate

Chemical Property of ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate

There total 1 articles about ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5S,6S)-6-((S)-1-(benzyloxy)ethyl)-5-methyltetrahydro-2H-pyran-2-one (1043451-54-2) + ethyl acetate (141-78-6) → ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate (1043451-62-2)

Guidance literature:

ethyl acetate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

(5S,6S)-6-((S)-1-(benzyloxy)ethyl)-5-methyltetrahydro-2H-pyran-2-one; In tetrahydrofuran; at -78 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/ol800902g

Reference yield:

ethyl 2-((5S,6S)-6-((S)-1-(benzyloxy)ethyl)-2-hydroxy-5-methyltetrahydro-2Hpyran-2-yl)ethanoate (1043451-62-2) → ethyl 2-((2R,5S,6S)-6-((S)-1-(benzyloxy)ethyl)-5-methyltetrahydro-2H-pyran-2-yl)ethanoate (1043451-56-4)

Guidance literature:

With triethylsilane; boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; for 0.25h; Inert atmosphere;

DOI:10.1021/ol800902g

upstream raw materials:

(5S,6S)-6-((S)-1-(benzyloxy)ethyl)-5-methyltetrahydro-2H-pyran-2-one

ethyl acetate

Downstream raw materials:

ethyl 2-((2R,5S,6S)-6-((S)-1-(benzyloxy)ethyl)-5-methyltetrahydro-2H-pyran-2-yl)ethanoate