Technology Process of 3β-O-benzylchlorogenin
There total 6 articles about 3β-O-benzylchlorogenin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-O-benzyl diosgenin;
With
diborane-dimethylsulfide complex;
In
tetrahydrofuran;
at 20 ℃;
With
sodium hydroxide; dihydrogen peroxide;
at 20 ℃;
DOI:10.1016/j.carres.2005.03.019
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 96 percent / NaH / tetrahydrofuran; dimethylformamide / Heating
2.1: B2H6*MeS2 / tetrahydrofuran / 20 °C
2.2: 71 percent / aq. NaOH; aq. H2O2 / 20 °C
With
diborane-dimethylsulfide complex; sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.carres.2005.03.019
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 90 percent / NaH, tetrabutylammonium iodide / tetrahydrofuran / 16 h / Heating
2: 1.) BH3-SMe2, 2.) H2O2, NaOH / 1.) THF, 0 deg C, 0.1 h, room temperature, 20 h, 2.) ethanol, water, reflux, 1 h
With
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
DOI:10.1021/jo980266c
