Technology Process of 5-(benzyloxy)-1-(cyclopropylmethyl)-4-iodo-1H-benzotriazole
There total 6 articles about 5-(benzyloxy)-1-(cyclopropylmethyl)-4-iodo-1H-benzotriazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: acetic acid / dichloromethane / 1.08 h / 10 °C
1.2: 18 h / 20 °C
2.1: hydrogen / 3percent Pt/0.6percentVG/C / ethanol / 2.5 h / 10 °C / 2068.65 Torr / Inert atmosphere
3.1: methanesulfonic acid; isopentyl nitrite / ethanol / 0.25 h
4.1: boron tribromide / dichloromethane / 0 - 20 °C
4.2: 14 h
4.3: pH < 5
5.1: N-iodo-succinimide / acetic acid / 0.25 h
6.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 50 °C
With
N-iodo-succinimide; methanesulfonic acid; hydrogen; boron tribromide; potassium carbonate; acetic acid; isopentyl nitrite;
3percent Pt/0.6percentVG/C;
In
ethanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen / 3percent Pt/0.6percentVG/C / ethanol / 2.5 h / 10 °C / 2068.65 Torr / Inert atmosphere
2.1: methanesulfonic acid; isopentyl nitrite / ethanol / 0.25 h
3.1: boron tribromide / dichloromethane / 0 - 20 °C
3.2: 14 h
3.3: pH < 5
4.1: N-iodo-succinimide / acetic acid / 0.25 h
5.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 50 °C
With
N-iodo-succinimide; methanesulfonic acid; hydrogen; boron tribromide; potassium carbonate; isopentyl nitrite;
3percent Pt/0.6percentVG/C;
In
ethanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
