2-phenylthioacetophenone tosylhydrazone

Base Information

• Chemical Name: 2-phenylthioacetophenone tosylhydrazone
• CAS No.: 19159-76-3
• Molecular Formula: C₂₁H₂₀N₂O₂S₂
• Molecular Weight: 396.534
• Mol file: 19159-76-3.mol

Synonyms:2-phenylthioacetophenone tosylhydrazone

Chemical Property of 2-phenylthioacetophenone tosylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenylthioacetophenone tosylhydrazone

There total 3 articles about 2-phenylthioacetophenone tosylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

thiophenol (108-98-5) + N′-(2-chloro-1-phenylethylidene)-4-methylbenzenesulfonohydrazide (71094-28-5) → 2-phenylthioacetophenone tosylhydrazone (19159-76-3)

Guidance literature:

With triethylamine; In tetrahydrofuran; at -78 ℃;

Reference yield:

1-chloroacetophenone (532-27-4,108321-66-0,164322-25-2) → 2-phenylthioacetophenone tosylhydrazone (19159-76-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / methanol / 8 h

2: 79 percent / Et₃N / tetrahydrofuran / -78 °C

With triethylamine; In tetrahydrofuran; methanol;

Reference yield:

toluene-4-sulfonic acid hydrazide (1576-35-8) → 2-phenylthioacetophenone tosylhydrazone (19159-76-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / methanol / 8 h

2: 79 percent / Et₃N / tetrahydrofuran / -78 °C

With triethylamine; In tetrahydrofuran; methanol;

upstream raw materials:

thiophenol

N′-(2-chloro-1-phenylethylidene)-4-methylbenzenesulfonohydrazide

1-chloroacetophenone

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

1-phenyl-2-(phenylthio)ethanone

(1S,2S)-3-Phenyl-3-phenylsulfanylmethyl-cyclopropane-1,2-dicarboxylic acid diethyl ester