Ketone, 2-ethyl-3-pyridyl methyl (8CI)

Base Information

• Chemical Name: Ketone, 2-ethyl-3-pyridyl methyl (8CI)
• CAS No.: 31931-75-6
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.192
• Mol file: 31931-75-6.mol

Synonyms:Ketone,2-ethyl-3-pyridyl methyl (8CI)

Chemical Property of Ketone, 2-ethyl-3-pyridyl methyl (8CI)

Chemical Property:

• Boiling Point: 47 - 48 °C (0.1 mmHg)
• PSA: 29.96000
• LogP: 1.84660

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Ethylpyridin-3-yl)ethanone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ketone, 2-ethyl-3-pyridyl methyl (8CI)

There total 2 articles about Ketone, 2-ethyl-3-pyridyl methyl (8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

3-hexyn-2-one (1679-36-3) + Propargylamine (2450-71-7) → 2-Ethyl-3-acetyl-pyridin (31931-75-6)

Guidance literature:

With dipotassium peroxodisulfate; silver trifluoromethanesulfonate; In toluene; at 80 ℃; for 6h; regioselective reaction; Sealed tube;

DOI:10.1016/j.tet.2017.09.002

Reference yield:

→ 2-Ethyl-3-acetyl-pyridin (31931-75-6)

Guidance literature:

Verb.IV, VII (R1=H, R2=CH3, R3=C2H5);

DOI:10.1016/0040-4020(70)80027-8

upstream raw materials:

3-hexyn-2-one

Propargylamine

Refernces