(E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

Base Information

• Chemical Name: (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate
• CAS No.: 115578-90-0
• Molecular Formula: C₁₅H₁₇Cl₂O₄P
• Molecular Weight: 363.177

Synonyms:(E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

Chemical Property of (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

There total 6 articles about (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

[1-(2,3-Dichloro-phenyl)-meth-(E)-ylidene]-isobutyl-amine (119672-85-4) + 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane (111011-80-4) → (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate (115578-90-0)

Guidance literature:

With acetic anhydride; In benzene; for 4h; Heating;

DOI:10.1248/cpb.36.1139

Reference yield: 25.0%

2,3-dichlorobenzylaldehyde (6334-18-5) + 2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane (111011-80-4) → (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate (115578-90-0)

Guidance literature:

piperdinium acetate; In benzene; Heating;

DOI:10.1248/cpb.35.4144

Reference yield: 11.0%

2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane (111011-80-4) + 1,2-dichloro-3-(dimorpholinomethyl)benzene → 2,3-dichlorobenzylaldehyde (6334-18-5) + (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate (115578-90-0) + (Z)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

Guidance literature:

With trifluoroacetic acid; Yield given. Multistep reaction. Title compound not separated from byproducts; 1) toluene, 2) r.t., 1.0 h;

DOI:10.1055/s-1993-25926

upstream raw materials:

2,3-dichlorobenzylaldehyde

2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane

[1-(2,3-Dichloro-phenyl)-meth-(E)-ylidene]-isobutyl-amine

2-methoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane

Downstream raw materials:

4-(2,3-Dichloro-phenyl)-5-(5,5-dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3-carboxylic acid 2-(benzyl-methyl-amino)-ethyl ester

4-(2,3-Dichloro-phenyl)-5-(5,5-dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 115578-90-0 (E)-2,2-dimethyl-1,3-propanediyl α-acetyl-2,3-dichlorostyrylphosphonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send