ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Base Information

Chemical Name:ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS No.:1315248-02-2
Molecular Formula:C₃₃H₄₀N₄O₈S₂
Molecular Weight:684.835
Hs Code.:

ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Synonyms:ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Suppliers and Price of ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

There total 2 articles about ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 101913-37-5
4-[3-(4-formyl-2-methoxyphenoxy)propoxy]-3-methoxybenzaldehyde

: 141-97-9
ethyl acetoacetate

: 17356-08-0
thiourea

: 1315248-02-2
ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Guidance literature:: With cerium(III) chloride heptahydrate; In acetonitrile; at 85 - 90 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2011.04.048

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 1315248-02-2
ethyl 4-[4-(3-(4-[5-(ethoxycarbonyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4-pyrimidinyl]-2-methoxyphenoxy)propoxy)-3-methoxyphenyl]-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; potassium iodide / acetonitrile / 48 h / 90 °C

2: cerium(III) chloride heptahydrate / acetonitrile / 85 - 90 °C / Inert atmosphere

With cerium(III) chloride heptahydrate; potassium carbonate; potassium iodide; In acetonitrile; 2: Biginelli pyrimidine synthesis;
DOI:10.1016/j.ejmech.2011.04.048