methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Base Information

Chemical Name:methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate
CAS No.:159249-03-3
Molecular Formula:C₂₆H₂₉NO₂
Molecular Weight:387.522
Hs Code.:

Synonyms:methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Suppliers and Price of methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Chemical Property:

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Technology Process of methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

There total 5 articles about methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: 159249-03-3
methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / butyllithium / tetrahydrofuran / 2 h / -78 °C

2: 1.) LDA / 1.) THF, -78 deg C, 1 h, 2.) -78 deg C to room temperature

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran;

Reference yield:

: 103-26-4,1754-62-7
Methyl cinnamate

: 159249-03-3
methyl (2R,3S,αR)-3-(N-benzyl-n-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / butyllithium / tetrahydrofuran / 2 h / -78 °C

2: 1.) LDA / 1.) THF, -78 deg C, 1 h, 2.) -78 deg C to room temperature

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran;