(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Base Information

Chemical Name:(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid
CAS No.:1025796-40-0
Molecular Formula:C₁₉H₂₄IN₃O₈
Molecular Weight:549.319
Hs Code.:

Synonyms:(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Suppliers and Price of (S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

There total 6 articles about (S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39028-25-6
2,5-dioxopyrrolidin-1-yl 4-iodobenzoate

: C₁₃H₂₁N₃O₉

: 1025796-40-0
(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b02022

Reference yield:

: (R)-6-((tert-butoxycarbonyl)amino)-2-(3-((S)-1,5-di(tert-butoxy)-1,5-dioxopentan-2-yl)ureido)hexanoic acid

: 1025796-40-0
(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

2: triethylamine / N,N-dimethyl-formamide / 2.5 h / 20 °C / Inert atmosphere

With triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.9b02022

Reference yield:

: 32677-01-3
L-glutamic acid di-tert-butyl ester hydrochloride

: 1025796-40-0
(S)-2-(3-((R)-1-carboxy-5-(4-iodobenzamido)pentyl)ureido)-pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 0.5 h / -78 - 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 24 h / 20 °C

3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

4: triethylamine / N,N-dimethyl-formamide / 2.5 h / 20 °C / Inert atmosphere

With triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.9b02022