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39028-25-6

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39028-25-6 Usage

General Description

N-succinimidyl 4-iodobenzoate is a chemical compound commonly used in bioconjugation and labeling reactions. It consists of a succinimide ester group and an iodobenzoate group, which allows it to react with amino groups on proteins and peptides to form stable amide bonds. This makes it a valuable tool in the fields of biochemistry and molecular biology, particularly in the labeling of proteins for fluorescence microscopy, western blotting, and other analytical techniques. Additionally, the iodobenzoate group can be useful for radiolabeling studies. Overall, N-succinimidyl 4-iodobenzoate is a versatile and widely used reagent for bioconjugation and labeling applications in biological research.

Check Digit Verification of cas no

The CAS Registry Mumber 39028-25-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,2 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 39028-25:
(7*3)+(6*9)+(5*0)+(4*2)+(3*8)+(2*2)+(1*5)=116
116 % 10 = 6
So 39028-25-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H8INO4/c12-8-3-1-7(2-4-8)11(16)17-13-9(14)5-6-10(13)15/h1-4H,5-6H2

39028-25-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,5-dioxopyrrolidin-1-yl) 4-iodobenzoate

1.2 Other means of identification

Product number -
Other names 4-iodobenzoic acid N-hydroxysuccinimidyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:39028-25-6 SDS

39028-25-6Relevant articles and documents

Copper-mediated radioiodination reaction through aryl boronic acid or ester precursor and its application to direct radiolabeling of a cyclic peptide

Kondo, Yuto,Kimura, Hiroyuki,Fukumoto, Chiaki,Yagi, Yusuke,Hattori, Yasunao,Kawashima, Hidekazu,Yasui, Hiroyuki

, p. 336 - 345 (2021/05/27)

A copper-mediated radioiodination using aryl boronic precursors is attracting attention as a solution to oxidative iododestannylation and nickel-mediated radioiodination drawbacks. The copper-mediated radiolabeling method allows radioiodination at room te

Synthesis and evaluation of novel radioiodinated PSMA targeting ligands for potential radiotherapy of prostate cancer

Alexoff, David,Choi, Seok Rye,Kung, Hank F.,Ploessl, Karl,Yao, Xinyue,Zha, Zhihao,Zhao, Ruiyue,Zhu, Lin

, (2020/01/31)

Radioligand therapy (RLT) using prostate-specific membrane antigen (PSMA) targeting ligands is an attractive option for the treatment of Prostate cancer (PCa) and its metastases. We report herein a series of radioiodinated glutamate-urea-lysine-phenylalan

Rapid Cu-Catalyzed [211At]Astatination and [125I]Iodination of Boronic Esters at Room Temperature

Reilly, Sean W.,Makvandi, Mehran,Xu, Kuiying,Mach, Robert H.

supporting information, p. 1752 - 1755 (2018/04/14)

Access to 211At- and 125I-radiolabeled compounds in excellent RCCs and RCYs was achieved in just 10 min at room temperature using a Cu catalyst. The reaction conditions are applicable to a broad class of aryl and heteroaryl boronic reagents with varying steric and electronic properties as well as late-stage astatination and iodination of anticancer PARP inhibitors. This protocol eliminates the traditional need for toxic organotin reagents, elevated temperatures, and extended reaction times, providing a more practical and environmentally friendly approach to developing α-emitting radiotherapeutics.

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