3-Amino-5,6-dimethylpyrazine-2(1H)-thione

Base Information

• Chemical Name: 3-Amino-5,6-dimethylpyrazine-2(1H)-thione
• CAS No.: 31613-88-4
• Molecular Formula: C₆H₉N₃S
• Molecular Weight: 155.224
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID001272458
• Mol file: 31613-88-4.mol

Synonyms:31613-88-4;3-Amino-5,6-dimethylpyrazine-2(1H)-thione;DTXSID001272458;3-amino-2-mercapto-5,6-dimethylpyrazine;3-Amino-5,6-dimethyl-2(1H)-pyrazinethione

Chemical Property of 3-Amino-5,6-dimethylpyrazine-2(1H)-thione

Chemical Property:

• PSA: 90.60000
• LogP: 1.54550
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 155.05171847
• Heavy Atom Count: 10
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(N=C(C(=S)N1)N)C

Technology Process of 3-Amino-5,6-dimethylpyrazine-2(1H)-thione

There total 1 articles about 3-Amino-5,6-dimethylpyrazine-2(1H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-Mercapto-3-amino-5,6-dimethyl-pyrazin (31613-88-4)

Guidance literature:

entspr.Aminopyrazinol 1c, P4S10;

DOI:10.1246/bcsj.46.1890

Reference yield:

(2-chloroethyl)dimethylamine hydrochloride (4584-46-7) + 2-Mercapto-3-amino-5,6-dimethyl-pyrazin (31613-88-4) → 3-(2-dimethylaminoethylthio)-5,6-dimethylpyrazin-2-amine (780709-62-8)

Guidance literature:

With sodium hydroxide; for 2h;

DOI:10.1071/CH9830983

Reference yield:

2-Mercapto-3-amino-5,6-dimethyl-pyrazin (31613-88-4) + methyl iodide (74-88-4) → 5,6-dimethyl-3-methylthiopyrazin-2-amine (87444-27-7)

Guidance literature:

With sodium hydroxide; for 0.25h;

DOI:10.1071/CH9830983

Downstream raw materials:

2,5,6-trimethylthiazolo<4,5-b>pyrazine

3-(2-dimethylaminoethylthio)-5,6-dimethylpyrazin-2-amine

5,6-dimethyl-3-methylthiopyrazin-2-amine

3-methoxy-5,6-dimethylpyrazin-2-amine