C₁₃H₁₅FOSi

Base Information

• Chemical Name: C₁₃H₁₅FOSi
• CAS No.: 457948-96-8
• Molecular Formula: C₁₃H₁₅FOSi
• Molecular Weight: 234.345
• Mol file: 457948-96-8.mol

Synonyms:C₁₃H₁₅FOSi

Chemical Property of C₁₃H₁₅FOSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₃H₁₅FOSi

There total 1 articles about C₁₃H₁₅FOSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-fluorophenyl)-N-methoxy-N-methylacetamide (457948-95-7) + trimethylsilylacetylene (1066-54-2) → C13H15FOSi (457948-96-8)

Guidance literature:

trimethylsilylacetylene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

2-(4-fluorophenyl)-N-methoxy-N-methylacetamide; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield: 84.0%

C13H15FOSi (457948-96-8) → C10H7FO (1013936-47-4)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; methanol; at -78 ℃; for 0.333333h;

DOI:10.1021/ja710013y

Reference yield: 26.0%

C13H15FOSi (457948-96-8) + dimethyl amine (124-40-3) → C12H14FNO

Guidance literature:

In ethanol; water; at 20 ℃; for 1h;

upstream raw materials:

2-(4-fluorophenyl)-N-methoxy-N-methylacetamide

trimethylsilylacetylene

Downstream raw materials:

C₁₀H₇FO

Refernces