benzyl 1-methylcycloprop-2-ene-1-carboxylate

Base Information

• Chemical Name: benzyl 1-methylcycloprop-2-ene-1-carboxylate
• CAS No.: 1041780-38-4
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.226
• Mol file: 1041780-38-4.mol

Synonyms:benzyl 1-methylcycloprop-2-ene-1-carboxylate

Chemical Property of benzyl 1-methylcycloprop-2-ene-1-carboxylate

Chemical Property:

Purity/Quality:

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Technology Process of benzyl 1-methylcycloprop-2-ene-1-carboxylate

There total 1 articles about benzyl 1-methylcycloprop-2-ene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-bromo-1-methyl-1-cyclopropanecarboxylic acid (292623-33-7) + benzyl bromide (100-39-0) → benzyl 1-methylcycloprop-2-ene-1-carboxylate (1041780-38-4)

Guidance literature:

2-bromo-1-methyl-1-cyclopropanecarboxylic acid; With potassium carbonate; In methanol;

With potassium tert-butylate; In dimethyl sulfoxide; at 50 ℃; for 2h;

benzyl bromide; In dimethyl sulfoxide; for 0.5h;

DOI:10.1021/ol8011138

Reference yield:

benzyl 1-methylcycloprop-2-ene-1-carboxylate (1041780-38-4) + d'hydroxy-2 teramethyl-4,4,5,5-dioxaphospholane-1,2,3 (58954-06-6) → C18H25O5P

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,1'-bis(diphenylphosphino)ferrocene; In 1,4-dioxane; at 25 ℃; for 1h; optical yield given as %de; diastereoselective reaction;

DOI:10.1021/ol8011138

upstream raw materials:

2-bromo-1-methyl-1-cyclopropanecarboxylic acid

benzyl bromide