4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone

Base Information

• Chemical Name: 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone
• CAS No.: 122266-00-6
• Molecular Formula: C₃₁H₅₀F₂O₂
• Molecular Weight: 492.734
• Mol file: 122266-00-6.mol

Synonyms:4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone

Chemical Property of 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone

There total 4 articles about 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

(trans-4-pentylcyclohexyl)acetyl chloride (84361-28-4) + 1,2-Difluoro-3-dodecyloxybenzene (122265-83-2) → 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone (122266-00-6)

Guidance literature:

With iron(III) chloride; In dichloromethane; Ambient temperature;

DOI:10.1002/hlca.19890720319

Reference yield:

2,3-difluorophenol (6418-38-8) → 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone (122266-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / K₂CO₃ / ethyl acetate / Heating

2: 21 percent / FeCl₃ / CH₂Cl₂ / Ambient temperature

With iron(III) chloride; potassium carbonate; In dichloromethane; ethyl acetate;

DOI:10.1002/hlca.19890720319

Reference yield:

1-dodecylbromide (143-15-7) → 4-(dodecyloxy)-2,3-difluorophenyl (trans-4-pentylcyclohexyl)methyl ketone (122266-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / K₂CO₃ / ethyl acetate / Heating

2: 21 percent / FeCl₃ / CH₂Cl₂ / Ambient temperature

With iron(III) chloride; potassium carbonate; In dichloromethane; ethyl acetate;

DOI:10.1002/hlca.19890720319

upstream raw materials:

(trans-4-pentylcyclohexyl)acetyl chloride

1,2-Difluoro-3-dodecyloxybenzene

2,3-difluorophenol

1-dodecylbromide

Downstream raw materials:

2,3-difluoro-4-<2-(trans-4-pentylcyclohexyl)ethyl>phenyl dodecyl ether

2,3-difluoro-4-<2-(trans-4-pentylcyclohexyl)ethyl>phenol