1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Base Information

Chemical Name:1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene
CAS No.:611210-60-7
Molecular Formula:C₆₀H₁₀₂N₄O₁₆S₂Si₄
Molecular Weight:1311.96
Hs Code.:

1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Synonyms:1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Suppliers and Price of 1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

There total 8 articles about 1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 623-24-5
1,4-bis(bromomethyl)benzene

: 611210-59-4
2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranoside

: 611210-60-7
1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 3h;
DOI:10.1016/S0040-4020(03)00820-2

Reference yield:

: 72075-74-2,72002-52-9
methyl 3-azido-2,3,6-trideoxy-α-D-arabino-hexopyranoside

: 611210-60-7
1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Guidance literature:: Multi-step reaction with 7 steps

1: 99 percent / BF₃*OEt₂ / 0.83 h / 0 °C

2: 80 percent / molecular sieves 4 Angstroem; NBS / acetonitrile / 0.25 h / 0 °C

3: 40 percent / imidazole / CH₂Cl₂ / 0.17 h / 0 °C

4: 99 percent / H₂ / Pd/CaCO₃ / ethanol / 16 h / 25 °C

5: 72 percent / K₂CO₃ / CH₂Cl₂ / 2 h / 25 °C

6: 100 percent / 2,6-lutidine / CH₂Cl₂ / 16 h / 40 °C

7: 41 percent / K₂CO₃ / dimethylformamide / 3 h / 25 °C

With 1H-imidazole; 2,6-dimethylpyridine; N-Bromosuccinimide; 4 A molecular sieve; boron trifluoride diethyl etherate; hydrogen; potassium carbonate; Lindlar's catalyst; In ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4020(03)00820-2

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 611210-60-7
1,4-bis((2-tert-butyldimethylsilyloxyethyl 4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-3-N-p-nitrobenzenesulfonylamino-α-D-arabino-hexopyranosid-3-yl)methyl)benzene

Guidance literature:: Multi-step reaction with 5 steps

1: 40 percent / imidazole / CH₂Cl₂ / 0.17 h / 0 °C

2: 99 percent / H₂ / Pd/CaCO₃ / ethanol / 16 h / 25 °C

3: 72 percent / K₂CO₃ / CH₂Cl₂ / 2 h / 25 °C

4: 100 percent / 2,6-lutidine / CH₂Cl₂ / 16 h / 40 °C

5: 41 percent / K₂CO₃ / dimethylformamide / 3 h / 25 °C

With 1H-imidazole; 2,6-dimethylpyridine; hydrogen; potassium carbonate; Lindlar's catalyst; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(03)00820-2