2-(4-tert-butylphenyl)-5-(2,5-dibromophenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(4-tert-butylphenyl)-5-(2,5-dibromophenyl)-1,3,4-oxadiazole
CAS No.:226883-47-2
Molecular Formula:C₁₈H₁₆Br₂N₂O
Molecular Weight:436.146
Hs Code.:
Mol file:226883-47-2.mol

Synonyms:2-(4-tert-Butylphenyl)-5-(2,5-dibromphenyl)-1,3,4-oxadiazol

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Chemical Property of 2-(4-tert-butylphenyl)-5-(2,5-dibromophenyl)-1,3,4-oxadiazole

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Technology Process of 2-(4-tert-butylphenyl)-5-(2,5-dibromophenyl)-1,3,4-oxadiazole

There total 2 articles about 2-(4-tert-butylphenyl)-5-(2,5-dibromophenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 1710-98-1
p-tert-butyl benzoyl chloride

: 496965-00-5
5-(2,5-dibromo-phenyl)-1H-tetrazole

: 226883-47-2
2-(4-tert-Butylphenyl)-5-(2,5-dibromphenyl)-1,3,4-oxadiazol

Guidance literature:: With pyridine; at 100 ℃; for 3h;

Reference yield:

: 57381-41-6
2,5-dibromophenyl cyanide

: 226883-47-2
2-(4-tert-Butylphenyl)-5-(2,5-dibromphenyl)-1,3,4-oxadiazol

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / NaN₃, NH₄Cl / dimethylformamide / Heating

2: 52 percent / pyridine / 3 h / 100 °C

With pyridine; sodium azide; ammonium chloride; In N,N-dimethyl-formamide;

Reference yield: 45.0%

: 74-85-1
ethene

: 226883-47-2
2-(4-tert-Butylphenyl)-5-(2,5-dibromphenyl)-1,3,4-oxadiazol

: 2-<(4-tert-Butyl)phenyl>-5-(2,5-divinylphenyl)-1,3,4-oxadiazol

Guidance literature:: With triethylamine; tris-(o-tolyl)phosphine; palladium diacetate; In N,N-dimethyl-formamide; at 100 - 120 ℃; under 22501.8 Torr;