57381-41-6

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Dibromobenzonitrile is used as an intermediate for the synthesis of various pharmaceuticals. Its high reactivity makes it a valuable component in the production of a wide range of medications.
Used in Dye Industry:
In the dye industry, 2,5-Dibromobenzonitrile is utilized as an intermediate for the synthesis of different types of dyes. Its unique chemical properties contribute to the development of various colorants used in various applications.
Used in Agrochemical Industry:
2,5-Dibromobenzonitrile is also used as an intermediate in the agrochemical industry for the synthesis of various agrochemicals. Its role in the production of these compounds helps to improve agricultural productivity and crop protection.
Used in Chemical Industry:
As a precursor for the production of organic compounds, 2,5-Dibromobenzonitrile plays a crucial role in the chemical industry. Its versatility in chemical reactions allows for the creation of a broad spectrum of organic compounds used in various sectors.

InChI:InChI=1/C7H3Br2N/c8-6-1-2-7(9)5(3-6)4-10/h1-3H

Upstream product

• 3638-73-1 2,5-dibromoaniline 
• 6952-59-6 3-cyanobromobenzene 
• 100-47-0 benzonitrile 

Downstream Products

• 610-71-9 2,5-dibromobenzoic acid 
• 496965-00-5 5-(2,5-dibromo-phenyl)-1H-tetrazole 
• 226883-47-2 2-(4-tert-Butylphenyl)-5-(2,5-dibromphenyl)-1,3,4-oxadiazol 
• 34560-28-6 2-vinylbenzonitrile 
• 5338-96-5 3-cyanostyrene 

Relevant academic research and scientific papers

Palladium-catalyzed highly selective ortho-halogenation (I, Br, Cl) of arylnitriles via sp2 C-H bond activation using cyano as directing group

A palladium-catalyzed ortho-halogenation (I, Br, Cl) of arylnitrile is described. The optimal reaction conditions were identified after examining various factors such as catalyst, additive, solvent, and reaction temperature. Using cyano as the directing group, the halogenation reaction gave good to excellent yields. The method is compatible to the arylnitriles with either electron-withdrawing or electron-donating groups. The reaction is available to the substrate in at least gram scale. The present method was successfully applied to the synthesis of the precursors of paucifloral F and isopaucifloral F.

The Synthesis and Transition Temperatures of Some Lateral Cyano-Substituted-1,1':4',1''-terphenyls

In recent years we have used palladium-catalysed cross-coupling procedures to prepare a large number of very interesting lateral mono- and di-fluoro-substituted terphenyls.Similar methodology has been applied in the synthesis of lateral cyano-substituted terphenyls to assess the extent to which the mesophases of such systems can tolerate the larger cyano group; the synthetic routes to these compounds are discussed in detail.The compounds with the lateral cyano-substituent in the centre ring have very low melting points and liquid crystal phases exhibited (SC, SA and nematic) are dependent on the terminal substituents.The compounds with the cyano-substituent at the edge of the terphenyl core are still quite low melting and they have very wide SA ranges. Keywords: lateral cyano-substitution, 1,1':4',1''-terphenyls, palladium-catalysed cross-coupling