2,2-dideuterioacetophenone

Base Information

• Chemical Name: 2,2-dideuterioacetophenone
• CAS No.: 74636-51-4
• Molecular Formula: C₈H₈O
• Molecular Weight: 122.135
• Mol file: 74636-51-4.mol

Synonyms:2,2-dideuterioacetophenone

Chemical Property of 2,2-dideuterioacetophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-dideuterioacetophenone

There total 13 articles about 2,2-dideuterioacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

phenylacetylene (536-74-3) → 2,2-dideuterioacetophenone (74636-51-4)

Guidance literature:

With d⁽⁴⁾-methanol; C₇₂H₇₆Au₂N₈O₄P₂⁽²⁺⁾*2CF₃O₃S^(1-); water; at 50 ℃; Inert atmosphere;

DOI:10.24820/ark.5550190.p010.320

Reference yield: 72.0%

1-styrenyloxytrimethylsilane (13735-81-4) → acetophenone-d1 (60507-03-1) + 2,2-dideuterioacetophenone (74636-51-4)

Guidance literature:

1-styrenyloxytrimethylsilane; With methyllithium; In diethyl ether; at 20 ℃; for 1h;

With tert-butyl alcohol-d;

DOI:10.1002/jlcr.519

Reference yield: 60.0%

acetophenone (98-86-2) → Acetophenone-methyl-d3 (17537-31-4) + acetophenone-d1 (60507-03-1) + 2,2-dideuterioacetophenone (74636-51-4)

Guidance literature:

With deuteriated sodium hydroxide; water-d2; for 72h; Reflux;

DOI:10.1021/ja910631u

upstream raw materials:

(C₆H₅(O₂CCH₃)C₂Tl(O₂CCH₃))2

acetophenone

acetophenone-d1

1-styrenyloxytrimethylsilane

Downstream raw materials:

Acetophenone-methyl-d3