7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one

Base Information

• Chemical Name: 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one
• CAS No.: 153718-76-4
• Molecular Formula: C₁₈H₁₆N₂O₄S
• Molecular Weight: 356.402
• Mol file: 153718-76-4.mol

Synonyms:7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one

Chemical Property of 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one

There total 40 articles about 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-(2-azidoethyl)-6,7-dimethoxy-1-[(4-methylphenyl)sulfonyl]indole → 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one (153718-76-4)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene; at 0 ℃; for 1.5h;

DOI:10.1021/ja0365330

Reference yield: 61.0%

3-(2-Azidoethyl)-6,7-dimethoxy-1-<(4-methylphenyl)sulfonyl>indole (153718-70-8) → 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one (153718-76-4)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene; In water; at 0 ℃; for 1h;

DOI:10.1039/a709099d

Reference yield: 60.0%

1,3,4,5-tetrahydro-7,8-dimethoxy-1-(4-methylbenzenesulfonyl)pyrrolo<4,3,2-de>quinoline (153718-75-3) → 7-Methoxy-1-<(4-methylphenyl)sulfonyl>-3,4-dihydropyrrolo<4,3,2-de>quinolin-8(1H)-one (153718-76-4)

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at 0 ℃; for 1h;

DOI:10.1021/ja00084a026

upstream raw materials:

6-Methoxy-3-<2-<<<2-(trimethylsilyl)ethoxy>carbonyl>amino>ethyl>-1-(p-toluenesulfonyl)indole-4,7-dione

1,3,4,5-tetrahydro-7,8-dimethoxy-1-(4-methylbenzenesulfonyl)pyrrolo<4,3,2-de>quinoline

1,5-Bis-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-pyrrolo[4,3,2-de]quinoline-7,8-dione

3-(2-Azidoethyl)-6,7-dimethoxy-1-<(4-methylphenyl)sulfonyl>indole

Downstream raw materials:

C₂₅H₂₁I₂N₃O₄S

C₂₅H₁₉I₂N₃O₄S

7-(3,5-dibromo-4-hydroxyphenethylamino)-1-tosyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one

N-tosyldiscorhabdin C