1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%

Base Information

• Chemical Name: 1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%
• CAS No.: 304477-40-5
• Molecular Formula: C11H10N2O
• Molecular Weight: 186.21
• Mol file: 304477-40-5.mol

Synonyms:1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%;1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE);1-Methyl-3-phenyl-1H-pyrazole-4-carboxaldehyde;1-Methyl-3-phenylpyrazole-4-carboxaldehyde;1H-Pyrazole-4-carboxaldehyde, 1-Methyl-3-phenyl-

Chemical Property of 1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%

Chemical Property:

• Vapor Pressure: 2.92E-05mmHg at 25°C
• Melting Point: 105℃
• Refractive Index: 1.593
• Boiling Point: 356.4 °C at 760 mmHg
• PKA: -0.36±0.10(Predicted)
• Flash Point: 169.4 °C
• PSA: 34.89000
• Density: 1.13 g/cm³
• LogP: 1.89960

Purity/Quality:

97% ^*data from raw suppliers

1-Methyl-3-phenyl-1H-pyrazole-4-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%

There total 4 articles about 1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N,N-Dimethyl-N-[1-methyl-3-phenyl-pyrazol-4-ylmethylen]ammonium-perchlorat → 1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde (304477-40-5)

Guidance literature:

With sodium hydrogencarbonate; In diethyl ether; at 20 ℃; for 3h;

Reference yield:

dimethyl sulfate (77-78-1) + 3-Phenyl-1H-pyrazole-4-carboxaldehyde (26033-20-5) → 1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde (304477-40-5)

Guidance literature:

With potassium carbonate; In acetonitrile; Reflux;

DOI:10.2174/1570180816666190325163117

Reference yield:

acetophenone (98-86-2) → 1-methyl-3-phenyl-1H-pyrazole-4-carbaldehyde (304477-40-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium acetate / water; ethanol / 50 °C

2.1: trichlorophosphate / 0.08 h / 0 - 5 °C

2.2: 5 h / 70 °C

3.1: potassium carbonate / acetonitrile / Reflux

With sodium acetate; potassium carbonate; trichlorophosphate; In ethanol; water; acetonitrile; 2.1: |Vilsmeier-Haack Formylation / 2.2: |Vilsmeier-Haack Formylation;

DOI:10.2174/1570180816666190325163117

upstream raw materials:

dimethyl sulfate

3-Phenyl-1H-pyrazole-4-carboxaldehyde

acetophenone semicarbazone

acetophenone

Downstream raw materials:

1-methyl-3-phenyl-1H-pyrazole

1,1,1,3,3,3-hexafluoropropan-2-yl 4-((1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl)piperazine-1-carboxylate

1-methyl-3-phenyl-1H-pyrazole-4-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 304477-40-5 1-METHYL-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE,97%

Send

Send

Metric Ton KG G Pound L ML

Send

Send