Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

Base Information

Chemical Name:Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.:304021-07-6
Molecular Formula:C₁₀H₂₁NO₃
Molecular Weight:203.282
Hs Code.:
Mol file:304021-07-6.mol

Synonyms:Carbamicacid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

Suppliers and Price of Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

PSA：58.56000
LogP:2.06140

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

There total 3 articles about Carbamic acid, [(1R)-1-ethyl-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 75-16-1
methylmagnesium bromide

: 856781-69-6
(2R)-N-(tert-butoxycarbonyl)-2-aminobutanal

: 304021-07-6,304021-06-5
tert-butyl ((3R)-2-hydroxypentan-3-yl)carbamate

Guidance literature:: In tetrahydrofuran; diethyl ether; toluene; at -78 - 20 ℃;
DOI:10.1021/ol702325e

Reference yield: 67.6%

: 346690-97-9
N-(tert-butoxycarbonyl)-2-aminobutanal

: 304021-07-6,304021-06-5
tert-butyl ((3R)-2-hydroxypentan-3-yl)carbamate

Guidance literature:: With methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃;

Reference yield:

: 193086-15-6
(1-(hydroxymethyl)propyl)carbamic acid tert-butyl ester

: 304021-07-6,304021-06-5
tert-butyl ((3R)-2-hydroxypentan-3-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; sulfur trioxide pyridine complex / dimethyl sulfoxide / 15 - 20 °C

2: methylmagnesium bromide / diethyl ether; tetrahydrofuran / 0 - 20 °C

With methylmagnesium bromide; sulfur trioxide pyridine complex; triethylamine; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide;