Tert-butyl (5-formylthiazol-2-yl)carbamate

Base Information

Chemical Name:Tert-butyl (5-formylthiazol-2-yl)carbamate
CAS No.:391668-77-2
Molecular Formula:C9H12 N2 O3 S
Molecular Weight:228.272
Hs Code.:2934100090
European Community (EC) Number:840-945-3
DSSTox Substance ID:DTXSID10693866
Mol file:391668-77-2.mol

Synonyms:391668-77-2;tert-butyl (5-formylthiazol-2-yl)carbamate;tert-butyl N-(5-formyl-1,3-thiazol-2-yl)carbamate;tert-butyl 5-formylthiazol-2-ylcarbamate;(5-Formyl-thiazol-2-yl)-carbamic acid tert-butyl ester;TERT-BUTYL N-(5-FORMYLTHIAZOL-2-YL)CARBAMATE;Carbamic acid, (5-formyl-2-thiazolyl)-, 1,1-dimethylethyl ester;tert-Butyl(5-formylthiazol-2-yl)carbamate;SCHEMBL640612;DTXSID10693866;LKFCHUSAPKBABQ-UHFFFAOYSA-N;MFCD09834789;AKOS015904480;AB52786;AS-53636;CS-0054089;FT-0685259;EN300-196145;P16795;tert-Butyl 5-formyl-1,3-thiazol-2-ylcarbamate;2-tert-butyloxycarbonylaminothiazole-5-carbaldehyde;A824436;J-524737;Z1505695592;TERT-BUTYL (5-FORMYL-1,3-THIAZOL-2-YL)CARBAMATE

Suppliers and Price of Tert-butyl (5-formylthiazol-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-ButylN-(5-Formyl-1,3-thiazol-2-yl)carbamate
100mg
$ 130.00

Matrix Scientific
tert-Butyl N-(5-Formylthiazol-2-yl)carbamate 97%
1g
$ 685.00

Frontier Specialty Chemicals
(5-Formyl-thiazol-2-yl)-carbamicacidtert-butylester
1g
$ 120.00

Frontier Specialty Chemicals
(5-Formyl-thiazol-2-yl)-carbamicacidtert-butylester
250mg
$ 40.00

Crysdot
tert-Butyl(5-formylthiazol-2-yl)carbamate 97%
5g
$ 831.00

Chemenu
tert-ButylN-(5-Formylthiazol-2-yl)carbamate 97%
5g
$ 777.00

Alichem
tert-Butyl(5-formylthiazol-2-yl)carbamate
1g
$ 228.48

AK Scientific
tert-Butyl5-formylthiazol-2-ylcarbamate
2.5g
$ 1557.00

AK Scientific
tert-Butyl5-formylthiazol-2-ylcarbamate
250mg
$ 422.00

AK Scientific
tert-Butyl5-formylthiazol-2-ylcarbamate
100mg
$ 335.00

Total 24 raw suppliers

Chemical Property of Tert-butyl (5-formylthiazol-2-yl)carbamate

Chemical Property:

Refractive Index:1.603
PKA:4.89±0.70(Predicted)
PSA：96.53000
Density:1.321g/cm³
LogP:2.37560
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:228.05686342
Heavy Atom Count:15
Complexity:252

Purity/Quality:

99%, ^*data from raw suppliers

tert-ButylN-(5-Formyl-1,3-thiazol-2-yl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=NC=C(S1)C=O

Technology Process of Tert-butyl (5-formylthiazol-2-yl)carbamate

There total 6 articles about Tert-butyl (5-formylthiazol-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1001419-37-9
tert-butyl [5-(hydroxymethyl)-1,3-thiazol-2-yl]carbamate

: 391668-77-2
tert-butyl (5-formylthiazol-2-yl)carbamate

Guidance literature:: With manganese(IV) oxide; In dichloromethane; ethyl acetate; at 20 ℃; for 14h;

Reference yield: 55.0%

: 1003-61-8
2-aminothiazole-5-carbaldehyde

: 24424-99-5
di-tert-butyl dicarbonate

: 391668-77-2
tert-butyl (5-formylthiazol-2-yl)carbamate

Guidance literature:: With dmap; In tetrahydrofuran; at 60 ℃; for 2h;
DOI:10.1021/acs.jmedchem.0c00967

Reference yield:

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 170961-15-6
tert-butyl 1,3-thiazole-2-yl-carbamate

: 391668-77-2
tert-butyl (5-formylthiazol-2-yl)carbamate

Guidance literature:: tert-butyl 1,3-thiazole-2-yl-carbamate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -10 ℃;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 ℃;