4-Cyclopropylphenylboronic acid

Base Information

Chemical Name:4-Cyclopropylphenylboronic acid
CAS No.:302333-80-8
Molecular Formula:C9H11BO2
Molecular Weight:161.996
Hs Code.:2931900090
European Community (EC) Number:828-108-0
DSSTox Substance ID:DTXSID60385961
Wikidata:Q72461059
Mol file:302333-80-8.mol

Synonyms:4-CYCLOPROPYLPHENYLBORONIC ACID;302333-80-8;(4-cyclopropylphenyl)boronic Acid;4-CYCLOPROPYL-BENZENEBORONIC ACID;Boronic acid, (4-cyclopropylphenyl)-;Boronic acid, B-(4-cyclopropylphenyl)-;MFCD01309064;4-Cyclopropyl-phenylboronic acid;(4-Cyclopropylphenyl)boronicacid;SCHEMBL938629;4-cyclopropyl phenylboronic acid;DTXSID60385961;YNLGFXOBRXSMJZ-UHFFFAOYSA-N;CCG-2660;AKOS006276750;AC-30698;AS-46749;SY020549;BB 0262050;CS-0040763;4-cyclopropyl-benzeneboronic acid, AldrichCPR;F10371;EN300-3219449;A899580;J-017837

Suppliers and Price of 4-Cyclopropylphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Cyclopropylphenylboronic acid
50mg
$ 333.00

TRC
4-CyclopropylphenylboronicAcid
500mg
$ 165.00

TRC
4-CyclopropylphenylboronicAcid
1g
$ 315.00

SynQuest Laboratories
4-Cyclopropyl-benzeneboronic acid 95%
1 g
$ 320.00

SynQuest Laboratories
4-Cyclopropyl-benzeneboronic acid 95%
250 mg
$ 114.00

Matrix Scientific
(4-Cyclopropylphenyl)boronic acid 95+%
250mg
$ 285.00

Matrix Scientific
(4-Cyclopropylphenyl)boronic acid 95+%
1g
$ 670.00

Crysdot
(4-Cyclopropylphenyl)boronicacid 95+%
1g
$ 370.00

Chemenu
(4-cyclopropylphenyl)boronicacid 0.95
1g
$ 78.00

ChemBridge Corporation
(4-cyclopropylphenyl)boronicacid 95%
250 mg
$ 121.00

Total 21 raw suppliers

Chemical Property of 4-Cyclopropylphenylboronic acid

Chemical Property:

Boiling Point:320.3 °C at 760 mmHg
PKA:8.74±0.10(Predicted)
Flash Point:147.5 °C
PSA：40.46000
Density:1.17 g/cm³
LogP:0.24380
Storage Temp.:Room temperature.
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:162.0852098
Heavy Atom Count:12
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

4-Cyclopropylphenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=C(C=C1)C2CC2)(O)O
Uses 4-Cyclopropylphenylboronic Acid is an intermediate used to prepare substituted indoles as PPAR-γ binding agents. It is also used in the synthesis of thienopyrimidine bisphosphonate inhibitors of farnesyl pyrophosphate synthase for potential bone resorption treatment.

Technology Process of 4-Cyclopropylphenylboronic acid

There total 4 articles about 4-Cyclopropylphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 5467-74-3
4-Bromophenylboronic acid

: 5-cyclopropyl-1-aza-5-germabicyclo[3.3.3]undecane

: 302333-80-8
(4-cyclopropylphenyl)boronic acid

Guidance literature:: With bis(3,5-bis(trifluoromethyl)phenyl)(2-(2,4,6-triisopropylphenyl)-1H-inden-3-yl)phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In acetonitrile; at 120 ℃; for 16h; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.9b02776

Reference yield: 60.0%

: 5419-55-6
Triisopropyl borate

: 1124-14-7
1-bromo-4-cyclopropylbenzene

: 302333-80-8
(4-cyclopropylphenyl)boronic acid

Guidance literature:: 1-bromo-4-cyclopropylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; toluene; at -70 ℃; for 0.5h;

Triisopropyl borate; In tetrahydrofuran; hexane; toluene; at -70 - -20 ℃;

With hydrogenchloride; In tetrahydrofuran; hexane; water; toluene; at -20 - 20 ℃;

Reference yield: 60.0%

: 5419-55-6
Triisopropyl borate

: 302333-80-8
(4-cyclopropylphenyl)boronic acid

Guidance literature:: 1-bromo-4-cyclopropylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; toluene; at -70 ℃; for 0.5h;

Triisopropyl borate; In tetrahydrofuran; hexane; toluene; at -70 - -20 ℃;

With hydrogenchloride; water; In tetrahydrofuran; hexane; toluene;