Technology Process of C18H26BrNO5
There total 8 articles about C18H26BrNO5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide;
In
N,N-dimethyl-formamide;
for 6h;
Inert atmosphere;
Cooling with ice;
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: N,N-dimethylformamide dineopentyl acetal / toluene / 3 h / Reflux
2: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 - 20 °C
3: silver trifluoroacetate; iodine / chloroform / 120 h / -60 °C
4: tetrakis(triphenylphosphine) palladium(0); lithium chloride / toluene / 6 h / 100 °C / Inert atmosphere
5: bromine / methanol; diethyl ether / 0.5 h / -70 °C
6: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C
With
1H-imidazole; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; bromine; iodine; silver trifluoroacetate; N,N-dimethylformamide dineopentyl acetal; lithium chloride;
In
tetrahydrofuran; methanol; diethyl ether; chloroform; N,N-dimethyl-formamide; toluene;