4-nitrophenylboronic dimethyl ester

Base Information

• Chemical Name: 4-nitrophenylboronic dimethyl ester
• CAS No.: 92203-81-1
• Molecular Formula: C₈H₁₀BNO₄
• Molecular Weight: 194.983
• Mol file: 92203-81-1.mol

Synonyms:4-nitrophenylboronic dimethyl ester

Chemical Property of 4-nitrophenylboronic dimethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 4-nitrophenylboronic dimethyl ester

There total 1 articles about 4-nitrophenylboronic dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → 4-nitrophenylboronic dimethyl ester (92203-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrafluoroboric acid / water / 0.17 h / 0 °C

1.2: 1 h / 0 °C

1.3: 20 °C / Inert atmosphere

2.1: 1 h / 0 - 20 °C / Inert atmosphere

With tetrafluoroboric acid; In water;

DOI:10.1016/j.tetlet.2014.01.080

Reference yield:

methanol (67-56-1) + 4-nitrophenylboronic dimethyl ester (92203-81-1) + oxygen (80937-33-3) → para-methoxynitrobenzene (100-17-4)

Guidance literature:

With copper(II) acetate monohydrate; at 27 ℃; for 6h; under 760 Torr;

DOI:10.1021/om300586p

Reference yield:

2,3-dimethyl-2,3-butane diol (76-09-5) + 4-nitrophenylboronic dimethyl ester (92203-81-1) → 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene (171364-83-3)

Guidance literature:

In diethyl ether; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.01.080

upstream raw materials:

4-nitro-aniline

Downstream raw materials:

para-methoxynitrobenzene

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene