[2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid

Base Information

Chemical Name:[2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid
CAS No.:389127-43-9
Molecular Formula:C9H15 N O2
Molecular Weight:169.22
Hs Code.:
DSSTox Substance ID:DTXSID10697723
Mol file:389127-43-9.mol

Synonyms:[2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid;389127-43-9;DTXSID10697723

Suppliers and Price of [2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-2-(2-PROPENYL)-2-CARBOXYMETHYL-PYRROLIDINE 95.00%
5MG
$ 503.84

Total 3 raw suppliers

Chemical Property of [2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid

Chemical Property:

PSA：38.33000
LogP:1.18650
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:169.110278721
Heavy Atom Count:12
Complexity:191

Purity/Quality:

98% ^*data from raw suppliers

(R)-2-(2-PROPENYL)-2-CARBOXYMETHYL-PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CCC1(CCCN1)CC(=O)O

Technology Process of [2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid

There total 7 articles about [2-(Prop-2-en-1-yl)pyrrolidin-2-yl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 220200-87-3
(2R,5R)-5-(2-propenyl)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]octane-4-one

: 129704-91-2
(R)-2-allylpyrrolidine-2-carboxylic acid hydrochloride

: 389127-43-9
(R)-methyl 2-allylpyrrolidine-2-carboxylate

: (R)-methyl 2-allylpyrrolidene-2-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; for 4h; Reflux;
DOI:10.1002/chem.201700747

Reference yield: 27.0%

: 121772-98-3
(R)-2-allylpyrrolidine-2-carboxylic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 389127-43-9
(R)-methyl 2-allylpyrrolidine-2-carboxylate

Guidance literature:: In methanol;
DOI:10.1016/j.bmcl.2010.07.020

Reference yield:

: 118916-60-2,97538-67-5
(2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one

: 389127-43-9
(R)-methyl 2-allylpyrrolidine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: LDA / tetrahydrofuran / -78 °C

2: HCl; NaHCO₃

With hydrogenchloride; sodium hydrogencarbonate; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1002/1521-3773(20010917)40:18<3361::AID-ANIE3361>3.0.CO;2-9