C₃₃H₄₆O₄Si

Base Information

• Chemical Name: C₃₃H₄₆O₄Si
• CAS No.: 1429470-10-9
• Molecular Formula: C₃₃H₄₆O₄Si
• Molecular Weight: 534.811
• Mol file: 1429470-10-9.mol

Synonyms:C₃₃H₄₆O₄Si

Chemical Property of C₃₃H₄₆O₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₄₆O₄Si

There total 8 articles about C₃₃H₄₆O₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C31H42O3Si (1429470-09-6) + chloromethyl methyl ether (107-30-2) → C33H46O4Si (1429470-10-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; chemoselective reaction;

DOI:10.1016/j.tetlet.2013.02.052

Reference yield:

(2S)-3-Benzyloxy-2-methyl-1-p-(toluenesulphonyloxy)propane (86951-92-0) → C33H46O4Si (1429470-10-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: dimethyl sulfoxide / 1 h / 20 °C

2.1: n-butyllithium / tetrahydrofuran / 3 h / -78 - 20 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

4.1: D-(-)-diisopropyl tartrate; titanium(IV) isopropylate; tert.-butylhydroperoxide / dichloromethane / 12 h / -20 °C / Molecular sieve

5.1: copper(l) iodide / diethyl ether / 3 h / -23 °C

5.2: 2 h / 20 °C

6.1: 1H-imidazole / dichloromethane / 0 - 20 °C

7.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; copper(l) iodide; lithium aluminium tetrahydride; n-butyllithium; D-(-)-diisopropyl tartrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.tetlet.2013.02.052

Reference yield:

(R)-3-(benzyloxy)-2-methylpropan-1-ol (63930-49-4) → C33H46O4Si (1429470-10-9)

Guidance literature:

Multi-step reaction with 8 steps

1.1: dichloromethane / 0 - 20 °C / Alkaline conditions

2.1: dimethyl sulfoxide / 1 h / 20 °C

3.1: n-butyllithium / tetrahydrofuran / 3 h / -78 - 20 °C

4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

5.1: D-(-)-diisopropyl tartrate; titanium(IV) isopropylate; tert.-butylhydroperoxide / dichloromethane / 12 h / -20 °C / Molecular sieve

6.1: copper(l) iodide / diethyl ether / 3 h / -23 °C

6.2: 2 h / 20 °C

7.1: 1H-imidazole / dichloromethane / 0 - 20 °C

8.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; copper(l) iodide; lithium aluminium tetrahydride; n-butyllithium; D-(-)-diisopropyl tartrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.tetlet.2013.02.052

upstream raw materials:

(R)-3-(benzyloxy)-2-methylpropan-1-ol

(2S)-3-Benzyloxy-2-methyl-1-p-(toluenesulphonyloxy)propane

(2R)-benzyl-(2-methylpent-4-ynyl) ether

C₃₁H₄₂O₃Si

Downstream raw materials:

(2R,4R,5S)-6-(tert-butyldiphenylsilyloxy)-4-(methoxymethoxy)-2,5-dimethylhexan-1-ol

(5R,6S)-6,10,10-trimethyl-5-((2R)-2-methylbut-3-enyl)-9,9-diphenyl-2,4,8-trioxa-9-silaundecane

3-((4S,5S)-5-((3R,5R,6S,E)-7-(tert-butyldiphenylsilyloxy)-5-(methoxymethoxy)-3,6-dimethylhept-1-enyl)-2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-ol

C₃₅H₅₆O₆Si