86951-92-0Relevant articles and documents
Toward the synthesis of tulearin C: Stereoselective synthesis of the C1-C18 macrolactone core
Yadav,Venkatesh,Swapnil,Prasad
, p. 2336 - 2339 (2013/06/27)
The asymmetric and convergent synthesis of fully functionalized macrocyclic core of tulearin C is described. Sharpless asymmetric epoxidation, Gillman's reaction, olefin cross metathesis, α aminoxylation, and ring closing metathesis reactions are the key
Total Synthesis of (+)-Carbonolide B
Keck, Gary E.,Palani, Anandan,McHardy, Stanton F.
, p. 3113 - 3122 (2007/10/02)
The macrolide (+)-carbonolide B, the aglycon of the antibiotic carbomycin B, was synthesized via a convergent sequence.A key step of the approach is the union of aldehyde 6 with stannane 7 in the presence of MgBr2*OEt2 as Lewis acid to afford the C1-C9 fr
A NEW APPROACH TO 1,7-DIOXASPIROUNDEC-4-ENES VIA METALLATED ALLENOL ETHERS. SYNTHESIS OF LACRIMIN A.
Takle, Andrew,Kocienski, Philip
, p. 4503 - 4516 (2007/10/02)
Key steps in the first total synthesis of Lacrimin A (2) include (a) the use of methoxyallene as an enone-1,3-dianion equivalent; (b) the use of a new copper-catalysed migratory insertion reaction to construct a tri-substituted alkene stereoselectively; and (c) the use of a Pd(0)-catalysed coupling reaction to generate an isochromanone ring.