2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester

Base Information

• Chemical Name: 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester
• CAS No.: 145655-18-1
• Molecular Formula: C₂₂H₂₂N₂O₁₄
• Molecular Weight: 538.422
• Mol file: 145655-18-1.mol

Synonyms:2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester

Chemical Property of 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester

There total 1 articles about 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nifedipine (21829-25-4) → 2-Hydroxymethyl-5-methoxycarbonyl-6-methyl-4-(2-nitrophenyl)-pyridin-3-carbonsaeure (34783-31-8) + Oxidized Nifedipine Monomethylester (73372-63-1) + 2-Methyl-4-(2-nitrophenyl)-5-oxo-5,7-dihydrofuro<3,4-b>pyridin-3-carbonsaeure (105378-62-9) + 6-Methyl-4-(2-nitro-phenyl)-pyridine-2,3,5-tricarboxylic acid 3,5-dimethyl ester (145655-14-7) + 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester (145655-16-9) + 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester (145655-18-1)

Guidance literature:

Product distribution; Mechanism; biotransformation in rat and dog (5 mg/kg body weight, oral and/or intraduodenal administration); ¹⁴C-labelling;

upstream raw materials:

nifedipine