2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester

Base Information

• Chemical Name: 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester
• CAS No.: 145655-16-9
• Molecular Formula: C₂₃H₂₄N₂O₁₃
• Molecular Weight: 536.449

Synonyms:2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester

Chemical Property of 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester

There total 1 articles about 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nifedipine (21829-25-4) → 2-Hydroxymethyl-5-methoxycarbonyl-6-methyl-4-(2-nitrophenyl)-pyridin-3-carbonsaeure (34783-31-8) + Oxidized Nifedipine Monomethylester (73372-63-1) + 2-Methyl-4-(2-nitrophenyl)-5-oxo-5,7-dihydrofuro<3,4-b>pyridin-3-carbonsaeure (105378-62-9) + 6-Methyl-4-(2-nitro-phenyl)-pyridine-2,3,5-tricarboxylic acid 3,5-dimethyl ester (145655-14-7) + 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-methyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester (145655-16-9) + 2-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxymethyl)-6-hydroxymethyl-4-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 3-methyl ester (145655-18-1)

Guidance literature:

Product distribution; Mechanism; biotransformation in rat and dog (5 mg/kg body weight, oral and/or intraduodenal administration); ¹⁴C-labelling;

upstream raw materials:

nifedipine

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