6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine

Base Information

• Chemical Name: 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine
• CAS No.: 275382-77-9
• Molecular Formula: C₁₈H₁₃BrClN₃O₂
• Molecular Weight: 418.677
• Mol file: 275382-77-9.mol

Synonyms:6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine

Chemical Property of 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine

There total 6 articles about 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-bromo-2-[N-(2-chloro-4-phenylbenzyl)acetamido]-3-nitropyridine (219767-13-2) → 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine (275382-77-9)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; water;

Reference yield:

phenylboronic acid (98-80-6) → 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine (275382-77-9)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; hexane; toluene

4: sodium hydroxide / 1,4-dioxane; water

With sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; hexane; water; toluene;

Reference yield:

2,6-dibromo-3-nitropyridine (55304-80-8) → 6-bromo-2-[N-(2-chloro-4-phenylbenzyl)amino]-3-nitropyridine (275382-77-9)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol; water

2: sulfuric acid; acetic anhydride / acetic acid

4: sodium hydroxide / 1,4-dioxane; water

With sodium hydroxide; sulfuric acid; acetic anhydride; In 1,4-dioxane; ethanol; water; acetic acid;

upstream raw materials:

6-bromo-2-[N-(2-chloro-4-phenylbenzyl)acetamido]-3-nitropyridine

2-(acetamido)-6-bromo-3-nitropyridine

2,6-dibromo-3-nitropyridine

3-chloro-4-methyl-1,1'-biphenyl