4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Base Information

Chemical Name:4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine
CAS No.:1242249-93-9
Molecular Formula:C₁₂H₅Cl₂FN₂S
Molecular Weight:299.156
Hs Code.:

Synonyms:4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Suppliers and Price of 4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Chloro-2-(2-chloro-6-fluorophenyl)-thiazolo[5,4-c]pyridine 97%
5g
$ 6480.00

Matrix Scientific
4-Chloro-2-(2-chloro-6-fluorophenyl)-thiazolo[5,4-c]pyridine 97%
1g
$ 2160.00

Total 1 raw suppliers

Chemical Property of 4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

4-Chloro-2-(2-chloro-6-fluorophenyl)-thiazolo[5,4-c]pyridine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

There total 6 articles about 4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1365991-98-5
2-chloro-N-(2-chloro-3-fluoro-pyridin-4-yl)-6-fluorobenzimidoyl chloride

: 1242249-93-9
4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Guidance literature:: 2-chloro-N-(2-chloro-3-fluoro-pyridin-4-yl)-6-fluorobenzimidoyl chloride; With pyridine; thiourea; In isopropyl alcohol; for 3.5h; Inert atmosphere; Reflux;

With triethylamine; In isopropyl alcohol; at 20 ℃; Reflux;

Reference yield:

: 79455-63-3
2-chloro-6-fluorobenzoyl chloride

: 1242249-93-9
4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / 1,4-dioxane / 6 h / 50 °C / Reflux

2.1: thionyl chloride / 16 h / Reflux

3.1: thiourea; pyridine / isopropyl alcohol / 3.5 h / Inert atmosphere; Reflux

3.2: 20 °C / Reflux

With pyridine; thionyl chloride; triethylamine; thiourea; In 1,4-dioxane; isopropyl alcohol;

Reference yield:

: 628691-93-0
2-chloro-3-fluoro-pyridine-4-carboxylic acid

: 1242249-93-9
4-chloro-2-(2-chloro-6-fluoro-phenyl)-thiazolo[5,4-c]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: diphenyl phosphoryl azide / toluene / 3 h / 110 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C

2.2: NH₂ cartridge

3.1: triethylamine / 1,4-dioxane / 6 h / 50 °C / Reflux

4.1: thionyl chloride / 16 h / Reflux

5.1: thiourea; pyridine / isopropyl alcohol / 3.5 h / Inert atmosphere; Reflux

5.2: 20 °C / Reflux

With pyridine; thionyl chloride; diphenyl phosphoryl azide; triethylamine; thiourea; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; isopropyl alcohol; toluene;