benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide

Base Information

• Chemical Name: benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide
• CAS No.: 1207668-84-5
• Molecular Formula: Br*C₃₉H₄₇N₄O₆
• Molecular Weight: 747.729
• Mol file: 1207668-84-5.mol

Synonyms:benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide

Chemical Property of benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide

There total 1 articles about benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-methyl-1H-imidazole (616-47-7) + benzyl (2S,4R)-4-(5-bromo-pentanoyloxy)-2-((S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl)-pyrrolidine-1-carboxylate (1207668-82-3) → benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide (1207668-84-5)

Guidance literature:

at 100 ℃; for 0.333333h;

DOI:10.1016/j.tet.2009.11.033

Reference yield: 95.0%

benzyl (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine-1-carboxylate bromide (1207668-84-5) → (2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine bromide (1207668-86-7)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In methanol; at 20 ℃; for 3h; under 760 Torr;

DOI:10.1016/j.tet.2009.11.033

upstream raw materials:

1-methyl-1H-imidazole

benzyl (2S,4R)-4-(5-bromo-pentanoyloxy)-2-((S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl)-pyrrolidine-1-carboxylate

Downstream raw materials:

(2S,4R)-4-(5-(1-methyl-1H-imidazol-3-ium-3-yl)pentanoyloxy)-2-[(S)-1-(hydroxy-diphenyl-methyl)-2-methyl-propylcarbamoyl]-pyrrolidine bromide