tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate

Base Information

• Chemical Name: tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate
• CAS No.: 1355612-24-6
• Molecular Formula: C₁₉H₂₈N₂O₂
• Molecular Weight: 316.444
• Mol file: 1355612-24-6.mol

Synonyms:tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate

Chemical Property of tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate

There total 2 articles about tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1-bromo-4-butene (5162-44-7) + tert-butyl 2-(but-3-enyl)-2-phenylhydrazinecarboxylate (1355612-19-9) → tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate (1355612-24-6)

Guidance literature:

With potassium carbonate; sodium hydroxide; In toluene; at 20 ℃;

DOI:10.1016/j.tet.2011.11.091

Reference yield:

tert-butyl 2-phenylhydrazine-1-carboxylate (42116-43-8) → tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate (1355612-24-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 - -40 °C / Inert atmosphere

1.2: 1 h / Inert atmosphere

2.1: potassium carbonate; sodium hydroxide / toluene / 20 °C

With n-butyllithium; potassium carbonate; sodium hydroxide; In tetrahydrofuran; hexane; toluene;

DOI:10.1016/j.tet.2011.11.091

Reference yield: 77.0%

tert-butyl 1,2-di(but-3-enyl)-2-phenylhydrazinecarboxylate (1355612-24-6) → tert-butyl 2-phenyl-3,4,7,8-tetrahydro-1,2-diazocine-1(2H)-carboxylate (1355612-35-9)

Guidance literature:

With Grubbs catalyst first generation; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tet.2011.11.091

upstream raw materials:

1-bromo-4-butene

tert-butyl 2-(but-3-enyl)-2-phenylhydrazinecarboxylate

tert-butyl 2-phenylhydrazine-1-carboxylate

Downstream raw materials:

tert-butyl 2-phenyl-3,4,7,8-tetrahydro-1,2-diazocine-1(2H)-carboxylate