tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane

Base Information

• Chemical Name: tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane
• CAS No.: 1358822-48-6
• Molecular Formula: C₃₃H₃₉BO₆
• Molecular Weight: 542.48
• Mol file: 1358822-48-6.mol

Synonyms:tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane

Chemical Property of tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane

There total 2 articles about tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

carbon dioxide (124-38-9,18923-20-1) + tris(4-bromo-2,3,5,6-tetramethylphenyl)borane (321735-68-6) → tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane (1358822-48-6)

Guidance literature:

tris(4-bromo-2,3,5,6-tetramethylphenyl)borane; With n-butyllithium; In tetrahydrofuran; at -78 - -60 ℃; for 1h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; for 1h; Inert atmosphere;

DOI:10.1002/anie.201901171

Reference yield:

1,2,4,5-tetramethylbenzene (95-93-2) → tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane (1358822-48-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bromine; iodine / dichloromethane / 1.5 h / Reflux

2.1: n-butyllithium / diethyl ether; hexane / 1 h / -78 - 0 °C / Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran / 1 h / -78 - -60 °C / Inert atmosphere

3.2: 1 h / Inert atmosphere

With n-butyllithium; bromine; iodine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane;

DOI:10.1002/anie.201901171

Reference yield: 72.0%

neodymium(III) chloride hexahydrate + tris(2',3',5',6'-tetramethylbiphenyl-4-carboxylic acid)borane (1358822-48-6) + potassium carbonate (584-08-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 4C33H36BO6(3-)*4Nd(3+)*2C3H7NO*14H2O*CO3(2-)*2C2H8N(1+)

Guidance literature:

In tetrahydrofuran; ethanol; at 80 ℃; for 48h; Sealed tube;

DOI:10.1021/ic400598x

upstream raw materials:

carbon dioxide

tris(4-bromo-2,3,5,6-tetramethylphenyl)borane

1,2,4,5-tetramethylbenzene