[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane

Base Information

• Chemical Name: [4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane
• CAS No.: 711013-46-6
• Molecular Formula: C₃₉H₆₈O₄Si
• Molecular Weight: 629.052
• Mol file: 711013-46-6.mol

Synonyms:[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane

Chemical Property of [4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane

There total 1 articles about [4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,2-Dimethyl-1,3-propanediol (126-30-7) + 2,5-bis(octyloxy)-4-[(triisopropylsilyl)ethynyl]benzaldehyde (350230-73-8) → [4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane (711013-46-6)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 24h; Heating;

DOI:10.1021/jo049939j

Reference yield: 84.0%

[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane (711013-46-6) → 2-(4-ethynyl-2,5-bis-octyloxy-phenyl)-5,5-dimethyl-[1,3]dioxane (711013-47-7)

Guidance literature:

[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 1h;

With water; In tetrahydrofuran;

DOI:10.1021/jo049939j

Reference yield:

[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-triisopropyl-silane (711013-46-6) → 12-bromo-dodecanoic acid {4-[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-phenyl}-amide (711013-49-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 0 °C

1.2: 84 percent / water / tetrahydrofuran

2.1: 59 percent / triethylamine; PdCl₂(PPh₃)2; CuI / 24 h / 20 °C

3.1: 2-chloro-4,6-dimethoxy-1,3,5-triazine; 4-methylmorpholine / tetrahydrofuran / 0.5 h / 0 °C

3.2: 91 percent / tetrahydrofuran / 3 h / 20 °C

With 4-methyl-morpholine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran;

DOI:10.1021/jo049939j

upstream raw materials:

2,2-Dimethyl-1,3-propanediol

2,5-bis(octyloxy)-4-[(triisopropylsilyl)ethynyl]benzaldehyde

Downstream raw materials:

2-(4-ethynyl-2,5-bis-octyloxy-phenyl)-5,5-dimethyl-[1,3]dioxane

4-[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-phenylamine

12-bromo-dodecanoic acid [4-(4-formyl-2,5-bis-octyloxy-phenylethynyl)-phenyl]-amide

12-bromo-dodecanoic acid {4-[4-(5,5-dimethyl-[1,3]dioxan-2-yl)-2,5-bis-octyloxy-phenylethynyl]-phenyl}-amide