2-(1,2,4-Oxadiazol-3-yl)pyridine

Base Information

• Chemical Name: 2-(1,2,4-Oxadiazol-3-yl)pyridine
• CAS No.: 13389-59-8
• Molecular Formula: C7H5 N3 O
• Molecular Weight: 147.136
• NSC Number: 109301
• DSSTox Substance ID: DTXSID90296430
• Nikkaji Number: J103.219D
• Wikidata: Q82037033
• Mol file: 13389-59-8.mol

Synonyms:2-(1,2,4-Oxadiazol-3-yl)pyridine;13389-59-8;3-pyridin-2-yl-1,2,4-oxadiazole;NSC109301;Pyridine, 2-(1,2,4-oxadiazol-3-yl)-;pyridyl-1,2,4-oxadiazole;SCHEMBL492799;DTXSID90296430;ZAAIEOSUVDRLGD-UHFFFAOYSA-N;AKOS025395183;NSC-109301;2-(1,2,4-Oxadiazol-3-yl)pyridine #

Chemical Property of 2-(1,2,4-Oxadiazol-3-yl)pyridine

Chemical Property:

• Vapor Pressure: 0.00379mmHg at 25°C
• Boiling Point: 289.6°Cat760mmHg
• PKA: -1.41±0.30(Predicted)
• Flash Point: 138.9°C
• Density: 1.255g/cm³
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 147.043261791
• Heavy Atom Count: 11
• Complexity: 131

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)C2=NOC=N2

Technology Process of 2-(1,2,4-Oxadiazol-3-yl)pyridine

There total 2 articles about 2-(1,2,4-Oxadiazol-3-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

imidazo[1,5-a]pyridine (274-47-5) → 3-(2'-pyridyl)-1,2,4-oxadiazole (13389-59-8)

Guidance literature:

With hydrogenchloride; sodium nitrite;

DOI:10.1021/jo01283a015

Reference yield:

2-pyridylamidoxime (1772-01-6) + O-acetyl pyridine 2-amidoxime (123865-76-9) → 3-(2'-pyridyl)-1,2,4-oxadiazole (13389-59-8)

Guidance literature:

With acetic anhydride; triethylamine; In chloroform; acetic acid;

upstream raw materials:

imidazo[1,5-a]pyridine

2-pyridylamidoxime

O-acetyl pyridine 2-amidoxime