methyl deuterated methyl(p-tolyl)sulfane

Base Information

• Chemical Name: methyl deuterated methyl(p-tolyl)sulfane
• CAS No.: 82244-59-5
• Molecular Formula: C₈H₁₀S
• Molecular Weight: 141.21
• Mol file: 82244-59-5.mol

Synonyms:methyl deuterated methyl(p-tolyl)sulfane

Chemical Property of methyl deuterated methyl(p-tolyl)sulfane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methyl deuterated methyl(p-tolyl)sulfane

There total 3 articles about methyl deuterated methyl(p-tolyl)sulfane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

carbon dioxide (124-38-9,18923-20-1) + para-thiocresol (106-45-6) → methyl deuterated methyl(p-tolyl)sulfane (82244-59-5)

Guidance literature:

carbon dioxide; para-thiocresol; With sodium borodeuteride; 18-crown-6 ether; at 80 ℃; for 0.5h; under 76.0051 Torr; Schlenk technique; Sealed tube;

With iodine; at 140 ℃; for 12h; Schlenk technique; Sealed tube;

DOI:10.1021/acs.joc.9b01180

Reference yield: 59.0%

4-methylbenzenediazonium tetrafluoroborate (459-44-9) + S-methyl-d3 sulfonothioate → methyl deuterated methyl(p-tolyl)sulfane (82244-59-5)

Guidance literature:

With potassium phosphate; eosin y; In methanol; at 30 ℃; for 22h; Glovebox; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.0c03562

Reference yield: 30.0%

d6-dimethyl sulfate (15199-43-6) + para-thiocresol (106-45-6) → methyl deuterated methyl(p-tolyl)sulfane (82244-59-5)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; at 20 ℃; for 19h;

DOI:10.1021/jo9914162

upstream raw materials:

d6-dimethyl sulfate

para-thiocresol

carbon dioxide

4-methylbenzenediazonium tetrafluoroborate

Downstream raw materials:

5-methyl-2-(⁽²⁾H₃)methylthiobenzaldehyde

4-methylphenyl methylsulfide