2-NAPHTHALENOL, 3-BROMO-

Base Information

• Chemical Name: 2-NAPHTHALENOL, 3-BROMO-
• CAS No.: 30478-88-7
• Molecular Formula: C10H7 Br O
• Molecular Weight: 223.069
• Hs Code.: 2908199090
• Mol file: 30478-88-7.mol

Synonyms:2-Naphthol,3-bromo- (7CI,8CI); 3-Bromo-2-naphthol

Chemical Property of 2-NAPHTHALENOL, 3-BROMO-

Chemical Property:

• Vapor Pressure: 0.000264mmHg at 25°C
• Melting Point: 82 °C
• Refractive Index: 1.704
• Boiling Point: 313.7°C at 760 mmHg
• PKA: 8.03±0.40(Predicted)
• Flash Point: 143.5°C
• PSA: 20.23000
• Density: 1.614g/cm³
• LogP: 3.30790
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromonaphthalen-2-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-NAPHTHALENOL, 3-BROMO-

There total 17 articles about 2-NAPHTHALENOL, 3-BROMO- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2‐bromo‐3‐methoxynaphthalene (68251-77-4) → 3-bromo-2-naphthol (30478-88-7)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 20 ℃;

DOI:10.1039/c2cc31960h

Reference yield: 55.0%

N,N-diethyl-O-((3-bromo)naphth-2-yl)-carbamate (1449272-81-4) → 3-bromo-2-naphthol (30478-88-7)

Guidance literature:

With zirconocene dichloride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol401547d

Reference yield:

2-Methoxynaphthalene (93-04-9) → 3-bromo-2-naphthol (30478-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: n-butyllithium; ethylene dibromide / tetrahydrofuran; hexane / -78 - 20 °C

2: boron tribromide / dichloromethane / -78 - 20 °C

With n-butyllithium; boron tribromide; ethylene dibromide; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1039/c2cc31960h

upstream raw materials:

2‐bromo‐3‐methoxynaphthalene

1,3-dibromonaphthalen-2-ol

3-bromonaphthalen-2-amine

3-bromo-2-hydroxy-naphthalene-1-diazonium-betaine

Downstream raw materials:

2-(benzyloxy)-3-bromonaphthalene

2-benzyloxy-3-(2-hydroxy-2-adamantyl)naphthalene

Refernces

• 1、 -. "TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND". Paragraph 0086; 0088. . Retrieved 2021/07/17.
• 2、 Liu, Wen-Bo,Usman, Muhammad,Wu, Lin-Yang. "Enantioselective iron/bisquinolyldiamine ligand‐catalyzed oxidative coupling reaction of 2‐naphthols". . . Retrieved 2020/02/25.