(E)-dihydrocinnamaldehyde trimethyl silyl enol ether

Base Information

• Chemical Name: (E)-dihydrocinnamaldehyde trimethyl silyl enol ether
• CAS No.: 51425-55-9
• Molecular Formula: C₁₂H₁₈OSi
• Molecular Weight: 206.36
• Mol file: 51425-55-9.mol

Synonyms:(E)-dihydrocinnamaldehyde trimethyl silyl enol ether

Chemical Property of (E)-dihydrocinnamaldehyde trimethyl silyl enol ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-dihydrocinnamaldehyde trimethyl silyl enol ether

There total 7 articles about (E)-dihydrocinnamaldehyde trimethyl silyl enol ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(E)-3-phenylpropenal (14371-10-9) + chloro-trimethyl-silane (75-77-4) → (E)-dihydrocinnamaldehyde trimethyl silyl enol ether (51425-55-9)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; copper(l) iodide; methyllithium; diisobutylaluminium hydride; In tetrahydrofuran; Product distribution; other α,β-unsaturated carbonyl compounds; var. temp. and reaction times;

DOI:10.1021/jo00379a024

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + chloro-trimethyl-silane (75-77-4) → (Z)-dihydrocinnamaldehyde trimethyl silyl enol ether (51425-56-0) + (E)-dihydrocinnamaldehyde trimethyl silyl enol ether (51425-55-9)

Guidance literature:

With magnesium; In N,N-dimethyl-formamide; at 15 - 25 ℃; Yield given; Yields of byproduct given;

DOI:10.1016/S0040-4039(98)02659-8

Reference yield:

3-Phenyl-2-phenylsulfanyl-1-trimethylsilanyl-propan-1-ol (105762-68-3,105762-69-4) → (E)-dihydrocinnamaldehyde trimethyl silyl enol ether (51425-55-9)

Guidance literature:

With lithium diisopropyl amide; In diethyl ether; at -78 - 25 ℃; Yield given;

DOI:10.1021/jo00378a038

upstream raw materials:

(E)-3-phenylpropenal

chloro-trimethyl-silane

3-Phenyl-2-phenylsulfanyl-1-trimethylsilanyl-propan-1-ol

bromobenzene

Downstream raw materials:

2-phenylacrolein

phenylacetaldehyde

(E)-3-phenylpropenal

2-allyl-3-phenylpropionaldehyde