4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

Base Information

Chemical Name:4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.
CAS No.:866026-35-9
Molecular Formula:C₁₃H₈ClF₄NO
Molecular Weight:305.659
Hs Code.:

Synonyms:4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

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Chemical Property of 4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

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Technology Process of 4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

There total 1 articles about 4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 1000531-85-0
3-(2-fluoro-4-trifluoromethyl-phenyl)-acrylamide

: 534-07-6
1,3-Dichloroacetone

: 866026-35-9
4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

Guidance literature:: In toluene; for 16h; Heating / reflux;

Reference yield: 70.0%

: 4-(2-[1,2,3]Triazol-1-yl-ethanesulfanylmethyl)-phenol

: 866026-35-9
4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

: 870534-51-3
1-[2-(4-{2-[2-(E)-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazol-4-ylmethoxy}-benzylsulfanyl)-ethyl]-1H-[1,2,3]triazole

Guidance literature:: 4-(2-[1,2,3]Triazol-1-yl-ethanesulfanylmethyl)-phenol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.; In DMF (N,N-dimethyl-formamide); at 65 ℃;

Reference yield: 64.0%

: 3-methyl-4-(2-[1,2,3]triazol-1-yl-ethanesulfanylmethyl)-phenol

: 866026-35-9
4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.

: 1-[2-(4-{2-[(E)-2-(2-Fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazol-4-ylmethoxy}-2-methyl-phenylmethanesulfanyl)-ethyl]-1H-[1,2,3]triazole

Guidance literature:: 3-methyl-4-(2-[1,2,3]triazol-1-yl-ethanesulfanylmethyl)-phenol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

4-chloromethyl-2-[2-(2-fluoro-4-trifluoromethyl-phenyl)-vinyl]-oxazole.; In DMF (N,N-dimethyl-formamide); for 12h;