6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Base Information

• Chemical Name: 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone
• CAS No.: 352426-45-0
• Molecular Formula: C₂₁H₂₄N₄O₂
• Molecular Weight: 364.447

Synonyms:6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Chemical Property of 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Chemical Property:

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Technology Process of 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

There total 1 articles about 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

6-<4-(3-bromopropionamido)phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone (111794-34-4) + benzylamine (100-46-9) → 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone (352426-45-0)

Guidance literature:

In propan-1-ol; ethanol;

Reference yield:

1-[2-methyl-4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-2,3-epoxypropane + 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone (352426-45-0) → 6-[4-[3-[2-hydroxy-3-[2-methyl-4-(2-(cyclopropylmethoxy)ethyl)phenoxy]-N-benzylpropylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:

In propan-1-ol;

Reference yield:

propan-1-ol (71-23-8) + 1-[2-(cyclopropyl-methoxy)-ethyl]-4-(2,3-epoxypropoxy)-benzene (63659-17-6) + 6-[4-(3-benzylaminopropionamido)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone (352426-45-0) → 6-[4-[3-[2-Hydroxy-3-[4-(2-(cyclopropylmethoxy)ethyl)-phenoxy[propylamino]propionamido]phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone + 6-<4-<3-phenoxy>-2-hydroxypropyl>amino>propionamido>phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone (111794-56-0)

Guidance literature:

upstream raw materials:

6-<4-(3-bromopropionamido)phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone

benzylamine

Downstream raw materials:

6-<4-<3-phenoxy>-2-hydroxypropyl>amino>propionamido>phenyl>-5-methyl-4,5-dihydro-3(2H)-pyridazinone

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