5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-

Base Information

Chemical Name:5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-
CAS No.:299917-02-5
Molecular Formula:C37H35 Br N4 O4
Molecular Weight:679.613
Hs Code.:

Synonyms:5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-

Suppliers and Price of 5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-

Chemical Property:

PSA：70.87000
LogP:8.17110

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl-

There total 1 articles about 5H-Pyrrolo3,2-dpyrimidin-2-amine, 7-bromo-N,N-bis(4-methoxyphenyl)methyl-4-(phenylmethoxy)-5-(phenylmethoxy)methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 824-94-2
p-methoxybenzyl chloride

: 299917-00-3
6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deazaguanine

: 299917-02-5
6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deaza-2-N,N-bis(4-methoxybenzyl)guanine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 16h;
DOI:10.1021/jo035744k

Reference yield: 72.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 299917-02-5
6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deaza-2-N,N-bis(4-methoxybenzyl)guanine

: 635319-13-0
7-benzyloxymethyl-6-O-benzyl-9-deaza-9-formyl-2-N-bis(4-methoxybenzyl)guanine

Guidance literature:: 6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deaza-2-N,N-bis(4-methoxybenzyl)guanine; With n-butyllithium; In diethyl ether; methoxybenzene; at -80 ℃; for 0.5h;

N,N-dimethyl-formamide; In diethyl ether; methoxybenzene; at -80 - 20 ℃;
DOI:10.1021/jm030305z

Reference yield: 15.0%

: 153172-33-9
(3aR,4R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-4,6a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyrrole

: 299917-02-5
6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deaza-2-N,N-bis(4-methoxybenzyl)guanine

: 1-β-(6-O-benzyl-7-N-benzyloxymethyl-9-deaza-2-N,N-bis-(4-methoxybenzyl)guanin-9-yl)-5-O-tert-butyldimethylsilyl-1,4-dideoxy-1,4-imino-2,3-O-isopropylidene-D-ribitol

Guidance literature:: 6-O-benzyl-7-N-benzyloxymethyl-9-bromo-9-deaza-2-N,N-bis(4-methoxybenzyl)guanine; With n-butyllithium; In diethyl ether; methoxybenzene; at -78 ℃;

(3aR,4R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-4,6a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyrrole; With tin(IV) chloride; In diethyl ether; methoxybenzene; at -78 ℃; for 2h;
DOI:10.1021/jo035744k