5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester

Base Information

• Chemical Name: 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester
• CAS No.: 128578-16-5
• Molecular Formula: C₂₁H₂₂O₆
• Molecular Weight: 370.402
• Mol file: 128578-16-5.mol

Synonyms:5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester

Chemical Property of 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester

There total 5 articles about 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

ethanol (64-17-5) + 5-(3-carboxybenzoyl)-2-hydroxybenzenepropanoic acid (117424-80-3) → 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester (128578-16-5)

Guidance literature:

With sulfuric acid; for 96h; Heating;

DOI:10.1021/jm00172a019

Reference yield:

5-(3-carboxybenzoyl)-2-hydroxybenzenepropanoic acid (117424-80-3) → 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester (128578-16-5)

Guidance literature:

In ethanol; sulfuric acid; ethyl acetate;

Reference yield:

3-carbethoxybenzoyl chloride (67326-20-9) → 5-[[3-(ethoxycarbonyl)phenyl]carbonyl]-2-hydroxybenzenepropanoic acid ethyl ester (128578-16-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 56 percent / AlCl₃ / CH₂Cl₂ / 1 h / 0 - 25 °C

2: 92 percent / pyridine hydrochloride / 4 h / 180 °C

3: 74 percent / sulfuric acid / 96 h / Heating

With aluminium trichloride; sulfuric acid; pyridine hydrochloride; In dichloromethane;

DOI:10.1021/jm00172a019

upstream raw materials:

ethanol

5-(3-carboxybenzoyl)-2-hydroxybenzenepropanoic acid

3-carbethoxybenzoyl chloride

2-methoxybenzenepropanoic acid ethyl ester

Downstream raw materials:

2-{[6-(4-Methoxyphenyl)-5-hexynyl]oxy}-5-[3-(ethoxycarbonyl)benzoyl]benzenepropanoic acid ethyl ester

2-{[6-(4-Acetylphenyl)hexyl]oxy}-5-[3(ethoxycarbonyl)benzoyl]benzenepropanoic acid ethyl ester

5-[(3-Carboxyphenyl)carbonyl]-2-[4-[(3,4-dihydro-4-oxo-8-propyl-2H-1-benzopyran-7-yl)oxy]butoxy]benzenepropanoic Acid

5-[(3-Carboxyphenyl)carbonyl]-2-[7-[(3,4-dihydro-4-oxo-8-propyl-2H-1-benzopyran-7-yl)oxy]heptyloxyl]benzenepropanoic Acid