N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester

Base Information

• Chemical Name: N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester
• CAS No.: 19792-09-7
• Molecular Formula: C₃₂H₄₄N₄O₉
• Molecular Weight: 628.723

Synonyms:N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester

Chemical Property of N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester

Chemical Property:

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Technology Process of N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester

There total 3 articles about N^α-tert.-Butyloxycarbonyl-N^δ-benzyloxycarbonyl-Orn-N^δ-benzyloxycarbonyl-Orn-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl N-δ-benzyloxycarbonyl-L-ornithinate (62631-17-8) + Boc-Orn(Z)-OH (2480-93-5) → Nα-tert.-Butyloxycarbonyl-Nδ-benzyloxycarbonyl-Orn-Nδ-benzyloxycarbonyl-Orn-methylester (19792-09-7)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran;

Reference yield:

N-(tert-butyloxycarbonyl) azide (1070-19-5) → Nα-tert.-Butyloxycarbonyl-Nδ-benzyloxycarbonyl-Orn-Nδ-benzyloxycarbonyl-Orn-methylester (19792-09-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / dioxane

2: DCC / tetrahydrofuran

With sodium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

N-carboxybenzyl-L-ornithine (3304-51-6,118578-06-6) → Nα-tert.-Butyloxycarbonyl-Nδ-benzyloxycarbonyl-Orn-Nδ-benzyloxycarbonyl-Orn-methylester (19792-09-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH / dioxane

2: DCC / tetrahydrofuran

With sodium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane;

upstream raw materials:

Methyl N-δ-benzyloxycarbonyl-L-ornithinate

Boc-Orn(Z)-OH

N-(tert-butyloxycarbonyl) azide

N-carboxybenzyl-L-ornithine

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